The Blood-Brain Barrier and Immune System Dysfunction in Neuroinflammatory Diseases
Received Date: Nov 01, 2024 / Published Date: Nov 30, 2024
Abstract
Neuroinflammatory diseases, encompassing a diverse group of conditions affecting the central nervous system (CNS), are characterized by immune cell infiltration and inflammation within the brain and spinal cord. A critical factor in this process is the blood-brain barrier (BBB), a highly selective barrier that regulates the passage of molecules and cells between the bloodstream and the CNS. This review examines the intricate relationship between BBB dysfunction and immune system activity in the pathogenesis of various neuroinflammatory diseases, highlighting the mechanisms involved and their therapeutic implications.
Citation: John D (2024) The Blood-Brain Barrier and Immune System Dysfunction in Neuroinflammatory Diseases. J Clin Exp Neuroimmunol, 9: 273. Doi: 10.4172/jceni.1000273
Copyright: © 2024 John D. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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