Abstract

Metabolomics, the comprehensive study of small-molecule metabolites within biological systems, is revolutionizing precision medicine by providing detailed insights into individual metabolic profiles. This article explores how bioanalytical approaches, such as mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, and chromatography, drive metabolomics to inform personalized therapies. These techniques enable the identification of disease-specific biomarkers, monitor treatment responses, and tailor interventions to patients’ unique biochemical states. Recent findings highlight their success in oncology, cardiology, and metabolic disorders, offering a pathway to optimized healthcare. Challenges like data complexity and standardization persist, but metabolomics promises to redefine therapeutic strategies, enhancing patient outcomes through individualized care.