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ISSN: 2329-9053

Journal of Molecular Pharmaceutics & Organic Process Research

  • Review Article   
  • J Mol Pharm Org Process Res 2015, Vol 3(3): 130
  • DOI: 10.4172/2329-9053.1000130

Traditional Ayurvedic medicines: Pathway to develop anti-cancer drugs

Murari Bhandari1, Anjaneya S Ravipati2, Narsimha Reddy2 and Sundar R Koyyalamudi3,4*
1School of Chemistry and Molecular Biosciences, University of Queensland, QLD 4072, Australia
2School of Science and Health, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia
3Institute of Endocrinology and Diabetes, Australia
4Discipline of Paediatrics and Child Health, The Children's Hospital at Westmead, The University of Sydney, Sydney, NSW 2145, Australia
*Corresponding Author : Sundar R Koyyalamudi, Discipline of Paediatrics and Child Health, The Children's Hospital at Westmead, The University of Sydney, NSW 2145, Australia, Tel: +61-2-98453185, Fax: +61-2-98453196, Email: [email protected]

Received Date: Dec 03, 2015 / Accepted Date: Dec 18, 2015 / Published Date: Dec 25, 2015

Abstract

Ayurveda, “life knowledge”, is an ancient Indian traditional medical system, which has been practiced for >5000 years and still in use with the same importance among many cultural tribes in Indian sub-continents. Ayurvedic medicine is a unique holistic approach to treatment where herbal medicines, special diets, yoga and relaxation methods, and lifestyle management are key strategies for curing various chronic diseases like diabetes, cancer, cardiovascular, neurological disorders and many other. Cancer is biologically complex disease, causing local damage and inflammation of cells due to lack of full response in a specific tissue that is responsible to maintain cellular differentiation, survival, proliferation and death. Studies have suggested that bioactive phytochemicals present in Ayurvedic plants (fruits, vegetables and herbs) mediate their effects by inhibiting some of the recently identified inflammatory pathways. Nevertheless, for successful implementation of Ayurvedic principles to drug discovery, major concerns relating to proportion, practicality, safety and drug interactions and possible side effects of newly developed Ayurvedic drugs and formulations need to be addressed. Systematic investigations of Ayurvedic drugs, employing contemporary scientific tools and methods, are expected to lead to the discoveries of major significance. Explorations involving studies of bioactive phytochemicals, their side effects, the specific potential targets and the mechanisms of action would transform this traditional therapeutic approach to standard Ayurvedic drug discovery which would be accepted and embraced by global populations. Current review focuses on the importance of anti-cancer drug discovery from Ayurvedic medicines in the modern context, ongoing improvements and major achievements in the field over the past decade or two.

Keywords: Ayurveda; Harmony; Balance

Citation: Bhandari M, Ravipati AS, Reddy N, Koyyalamudi SR (2015) Traditional Ayurvedic medicines: Pathway to develop anti-cancer drugs. J Mol Pharm Org Process Res 3: 130. Doi: 10.4172/2329-9053.1000130

Copyright: ©2015 Koyyalamudi SR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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