ISSN: 2161-1165

Epidemiology: Open Access
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  • Research Article   
  • Epidemiology (Sunnyvale) 2016, Vol 6(2): 234
  • DOI: 10.4172/2161-1165.1000234

Associated Complex of Urine Creatinine, Serum Creatinine, and Chronic Kidney Disease

Ram B. Jain*
Private Consultant, , Dacula, Ga 30019, USA
*Corresponding Author : Ram B. Jain, 2959 Estate View Court, Dacula, GA 30019, USA, Tel: 1-910-729-1049, Email: Jain.ram.b@gmail.com

Received Date: Mar 14, 2016 / Accepted Date: Mar 28, 2016 / Published Date: Apr 04, 2016

Abstract

Background: Impaired kidney function can affect levels of urine (UCR) and serum creatinine (SCR).

Objective: Data from National Health and Nutrition Examination Survey for the years 1999-2014 were used to study associations between UCR, SCR, and chronic kidney disease (CKD) stages 1-5.

Results: Levels of SCR and UCR were positively correlated for CKD Stages 1-3 and negatively correlated for CKD Stages 4 and 5. Males had higher levels of UCR than females but male-female differences were narrower for CKD Stages 1-3 than for CKD Stages 4-5. Males had higher levels of SCR than females but male-female differences were 30% for CKD Stages 1-3 and 20% for CKD Stages 4-5. NHB had higher levels of UCR than NHW but these differences were 27.5 mg/dL for CKD Stages 1-3 and 17.9 mg/dL for CKD Stage 4 and 5. NHB had about 11% higher SCR levels than NHW for CKD Stages 1-3 and about 20% higher levels than NHW for CKD Stages 4-5. For CKD Stages 1-3, levels of UCR decreased with increase in CKD Stage but levels of SCR increased with increase in CKD Stage. Levels of both SCR and UCR were higher for CKD Sage 5 than for CKD Stage 4.

Conclusions: CKD stages affect association between SCR and UCR as well as gender and racial/ethnic differences in both UCR and SCR.

Keywords: Chronic kidney disease; Albumin creatinine ratio; Diabetes; Serum creatinine; Gender; Race/Ethnicity; Ageing

Citation: Jain RB (2016) Associated Complex of Urine Creatinine, Serum Creatinine, and Chronic Kidney Disease. Epidemiology (Sunnyvale) 6:234. Doi: 10.4172/2161-1165.1000234

Copyright: © 2016 Jain RB. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Review summary

  1. Fabian Ewart
    Posted on Oct 03 2016 at 5:09 pm
    The aim of the study to investigate the relation of the urine and serum creatinine levels with the kidney function. The authors have accessed data from National Health and Nutrition Examination Survey and analysed the association between urine and serum creatinine levels and chronic kidney disease(CKD) in many different groups of people and different of stages of disease. Finally in short, the study concluded that there is relation between the CKD stages and SCR ,and UCR. The extensive data from the National Health and Nutrition Examination Survey was analysed very well and the article was written nicely.
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