alexa
Reach Us +1(631)596-0675
Change in Bowel Habit and Heme Positive Stool | OMICS International
ISSN: 2161-069X
Journal of Gastrointestinal & Digestive System

Like us on:

Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business

Change in Bowel Habit and Heme Positive Stool

Ayokunle T Abegunde*, Ravindranauth N. Sawh and Kenneth J. Vega

Department of Medicine, Oklahoma University Health Sciences Center, 920 Stanton L Young Boulevard, Oklahoma City, Oklahoma 73104, USA

*Corresponding Author:
Ayokunle T Abegunde, MB, BS, MSc
MRCGP, Gastroenterology Fellow
Section of Digestive Diseases and Nutrition
WP1345, Department of Medicine
Oklahoma University Health Sciences Center
920 Stanton L Young Boulevard, Oklahoma City
Oklahoma 73104, USA
Tel: (405) 271-8001
Fax: (405) 271-5803
E-mail: [email protected]

Received date: April 2, 2015; Accepted date: April 4, 2015; Published date: April 10, 2015

Citation: Abegunde A, Sawh RN, Vega KJ (2015) Change in Bowel Habit and Heme Positive Stool. J Gastrointest Dig Syst 5:i104. doi:10.4172/2161-069X.1000i104

Copyright: © 2015 Abegunde AT, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Gastrointestinal & Digestive System

Image Article

A 70 year old man was referred for out-patient colonoscopy because of two months history of change in bowel habit, weight loss and heme positive stool. Past medical history was significant for COPD, depression, alcohol dependence, and hypertension.

Colonoscopy revealed normal appearing mucosa in the entire colon and a 5mm sessile polyp (Figure 1) was found in the rectum on retroflexion. Random biopsies were obtained throughout the colon and the rectal polyp was completely excised. Histopathology of random colon biopsies (Figure 2) showed surface epithelial attenuation associated with increased numbers of intraepithelial and lamina propria lymphocytes (>20p/hf) consistent with lymphocytic colitis (LC).

gastrointestinal-digestive-system-rectal-mass

Figure 1: 5 mm rectal mass found on retro flexion.

gastrointestinal-digestive-system-colon-biopsy

Figure 2: Histopathology of random colon biopsy.

Histopathology of the rectal polyp (Figure 3) showed colonic mucosa with mild hyperplastic changes, and a 5 mm tumor composed of solid nests of small cytologically bland epithelioid cells. Immunohistochemical stains (Figure 4) were positive for synaptophysin and negative for chromogranin consistent with a carcinoid tumor.

gastrointestinal-digestive-system-rectal-polyp

Figure 3: Histopathology of the rectal polyp.

gastrointestinal-digestive-system-special-stain

Figure 4: Histopathology of the rectal polyp with special stain Synaptophysin.

LC is a type of microscopic colitis characterized by chronic, watery, diarrhea and increased subepithelial lymphocytes on colon biopsies [1]. The etiology of LC is unknown and it is typically associated with a normal endoscopic appearance [1]. LC has not been associated with an increased risk of colorectal cancer [1]. The rectal carcinoid does not explain the patient’s symptoms of chronic diarrhea and weight loss but may explain the heme positive stool.

Rectal carcinoids represent 1.3% of all rectal tumors; they are usually asymptomatic but may present with rectal pain, bleeding, or constipation; development of the typical carcinoid syndrome is rare [2]. Size of rectal carcinoids correlates with aggressiveness and metastatic potential. Recent series have shown that tumors smaller than 1 cm rarely metastasize, while lymph node and liver metastases are seen in up to 70% of cases if the tumor exceeds 2cm [3].

This case illustrates the fact that change in bowel habits associated with heme positive stool does not always signify colon cancer.

References

Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Article Usage

  • Total views: 12638
  • [From(publication date):
    April-2015 - Mar 29, 2020]
  • Breakdown by view type
  • HTML page views : 8838
  • PDF downloads : 3800
Top