Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar
Reach Us +447482874092


Therapeutic Ultrasound: Finding the Sweet Spot for Bioburden Control and Wound Healing | OMICS International
ISSN: 2165-7025
Journal of Novel Physiotherapies
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business

Therapeutic Ultrasound: Finding the Sweet Spot for Bioburden Control and Wound Healing

Teresa A. Conner-Kerr*
Department of Physical Therapy, School of Health Sciences, Winston-Salem State University
Corresponding Author : Teresa A. Conner-Kerr
Department of Physical Therapy
School of Health Sciences
Winston-Salem State University, USA
Tel: (336)750-2193
Received February 16, 2012; Accepted February 16, 2012; Published February 19, 2012
Citation: Conner-Kerr TA (2012) Therapeutic Ultrasound: Finding the Sweet Spot for Bioburden Control and Wound Healing. J Nov Physiother 2:e109. doi:10.4172/ 2165-7025.1000e109
Copyright: © 2012 Conner-Kerr TA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Novel Physiotherapies

Clinically, therapeutic ultrasound has been used by rehabilitation experts in physical therapy and other fields for more than 60 years [1]. Therapeutic indications have included a wide range of conditions (acute and chronic inflammation, tissue healing and repair, scar management, pain modulation and bone healing). Over the past six decades, high frequency ultrasound in the 1-3.3 MHz (1,000,000 to greater than 3,000,000 cycles per second) range has been primarily used in treating these conditions. However, in the past decade, we have seen the introduction of low frequency ultrasound for the management of nonhealing, recalcitrant wounds. Low frequency ultrasound (LFU) generators (<100,000 and > 20,000 hertz) are used for debridement [2], bioburden control [3] and to stimulate wound healing [4] through both non-contact and jet-spray modes of delivery.
A review of the research examining the effects of LFU, demonstrates an evolving body of evidence to suggest a sweet spot in the frequency range for killing wound pathogens, enhancing antibiotic effectiveness and stimulating human cells. Work by a number of investigators has demonstrated the effectiveness of 25- 35 kHz LFU in killing common wound pathogens [3,5,6] as well as antibiotic resistant species [3,6]. Thirty five kHz LFU also appeared to re-sensitize Methicillin-resistant Staphylococcus aureus to methicillin in vitro [3]. Similarly, other work has demonstrated that LFU in higher frequency ranges (67 kHz) enhances the effectiveness of antibiotics when bacteria are treated with the two modalities (antibiotic and LFU in combination) [7]. However, at this higher frequency, LFU does not directly kill bacteria. Interesting in the intermediate range of 40 kHz, an average reduction of 33% of bacteria was seen after 5 minutes of treatment with LFU in vitro compared to 99.99% with 180 seconds using 35 kHz [8]. Forty kHz LFU treatment also increased the number of Methicillin-resistant Staphylococcus aureus in vitro. This finding was not observed with frequencies at or below 35 kHz.
When reviewing the literature, there are reports across both 35 and 40 kHz frequencies in regards to mammalian cell stimulation. Conner-Kerr demonstrated a positive effect on a human neuronal monolayer development in vitro along with enhanced fibroblast migration rates in vitro for both 35 and 40 kHz [3,9,10]. As mentioned previously, human clinical trials have also demonstrated increased healing rates with LFU at the 40 kHz frequency [4]. Taken together, the evolving literature appears to indicate that there is a potential sweet spot for achieving both microbial control and cellular stimulation for wound healing and this sweet spot appears to be 35 kHz. Much research is yet to be done, however, the picture that is emerging points to select frequencies for achieving both bioburden control as well as wound healing. This sweet spot may be 35 kHz. Frequencies above 35 kHz do not appear to be as effective at bacterial killing. However, research demonstrates consistently positive results in facilitating wound healing. Reversal of antibiotic resistance has not been demonstrated at any frequency other than 35 kHz. Antibiotic effectiveness has been enhanced at 67 kHz without the concomitant effect of direct bacterial killing.
The above research has shifted the treatment paradigm for physical therapist and others who employee ultrasound to enhance healing. Practice has moved away from high frequency ultrasound to units that are based on low frequencies. The degree of debridement appears to be governed by the acoustic energy delivery method with the lower frequencies (35 kHz and below) used primarily in debridement. As the technology evolves, as well as our understanding of the mechanisms that underlies treatment effects, we will likely find that the clinical utility of LFU will expand.


Post your comment

Share This Article

Article Usage

  • Total views: 5513
  • [From(publication date):
    March-2012 - Apr 18, 2024]
  • Breakdown by view type
  • HTML page views : 1161
  • PDF downloads : 4352