Acinar Cell Carcinoma of the Pancreas with Liver Involvement: A Case of Report | OMICS International| Abstract

Journal of Biological and Medical Sciences
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Case Report   
  • J Biol Med Sci 2018, Vol 2(1): 106

Acinar Cell Carcinoma of the Pancreas with Liver Involvement: A Case of Report

Zhang X, Lin Q, Liu G, Fang Q, Xie K and Liu FB*
Department of Surgery and Organ Transplant Center, Anhui Medical University, China
*Corresponding Author : Liu FB, Department of Surgery and Organ Transplant Center, First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, 230022, Hefei Anhui Province, P.R. China, Tel: +86-18109691866, Email: [email protected]

Received Date: Jan 15, 2018 / Accepted Date: Jan 19, 2018 / Published Date: Jan 20, 2018


Objective: To investigate the clinic pathologic features, diagnosis, differential diagnosis, treatment and prognosis of the pancreatic acinar cell carcinoma.
Methods: The clinical data, pathomorphology and immunohistochemical staining of one patient case of Pancreatic cell carcinoma with liver involvement treated by Pancreaticoduodenectomy and partial hepatectomy at the first Affiliated Hospital of Anhui Medical University in April 2016 was analyzed retrospectively.
Results: Iconography scan of the abdomen or the whole body demonstrated a pancreatic mass and liver masses, with celiac Lymph node enlargement in a 58-years old female.
Microscopic examination showed that the pancreatic and liver tumor cells were trabecular and micro-glandular arrangement by biopsy; tumor cells were round or polygonal, and cytoplasm was rich, eosinophilic and granular, and some parts were vesicular, nuclei were mostly located in the base and round and oval; a large number of eosinophil’s were found in the interstitial infiltrating, rich eosinophilic granules were also found in their cytoplasm, and nuclei were slightly atypia
Immuno-histochemical staining showed that tumor cells were CgA (-), α-ACT (+), NSE (+/-) Ki-67 (index about 15%) and Syn (-).
Conclusion: Although acinar cell carcinoma of the pancreas has distinct characteristics on imaging and elevated AFP, correct diagnosis was difficult to determine preoperatively according image logical and laboratory examination. We should consider pancreatic cancer in the differential diagnosis of similar cases.

Keywords: Acinar cell carcinoma; Pancreas; Pathology; Clinical; Immunohistochemistry

Citation: Zhang X, Lin Q, Liu G, Fang Q, Xie K, et al. (2018) Acinar Cell Carcinoma of the Pancreas with Liver Involvement: A Case of Report. J Biol Med Sci 2: 106.

Copyright: © 2018 Zhang X, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Select your language of interest to view the total content in your interested language

Post Your Comment Citation
Share This Article
Recommended Conferences

12th International Conference on Alternative Medicine

Zurich, Switzerland
Article Usage
  • Total views: 5946
  • [From(publication date): 0-2018 - Sep 17, 2021]
  • Breakdown by view type
  • HTML page views: 5737
  • PDF downloads: 209