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Journal of Neuroinfectious Diseases
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  • Case Report   
  • J Neuroinfect Dis ,

An Unusual Presentation of Guillain -Barre Syndrome: A Case Study

Ananya Vasudhar*
S.S. Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, India
*Corresponding Author : Ananya Vasudhar, S. S. Institute of Medical Sciences and Research Centre, #15 Byrasandra Main Road, Jayanagar 1st Block East, Bengaluru, Karnataka, India, Tel: +91 9845022018, Email: ananyavasudhar@gmail.com

Received Date: Nov 30, 2020 / Accepted Date: Nov 14, 2020 / Published Date: Dec 21, 2020

Abstract

Guillain-Barré syndrome (GBS) is an acute postinfectious polyneuropathy characterized by symmetric and ascending flaccid paralysis. GBS most commonly presents with symmetrical proximal muscle weakness of the lower extremities as the first sign and moves upwards as ascending paralysis. This case presented with asymmetrical descending paralysis and altered sensorium, which made the initial diagnosis quite challenging. CSF reports revealed an albuminocytologic dissociation that supported the diagnosis of post-infectious Guillain-Barré syndrome. Nerve conduction studies revealed an abnormal with increased F wave latency, suggestive of right upper limb sensory and lower limb motor axonal and demyelinating neuropathy. The patient was treated with IVIG and other supportive treatment. The patient showed significant improvement within two weeks.

Background: Guillain-Barré syndrome (GBS) can be described as a collection of clinical syndromes that manifests as an acute inflammatory polyradiculoneuropathy with resultant weakness and diminished reflexes. Rarely does the disease manifest with descending paralysis. We present a case of GBS that on the initial presentation had symptoms of altered sensorium and asymmetrical descending paralysis.

Objective: An unusual presentation

Conclusions: Guillain Barre Syndrome often presents with a wide range of symptoms, although it usually presents with symmetrical ascending paralysis, this case presented with asymmetrical descending paralysis and altered sensorium, which made the initial diagnosis quite challenging.

Keywords: Acute inflammatory demyelinating polyneuropathy; Acute motor axonal neuropathy; Acute paralytic neuropathy; Guillain– Barré syndrome; IVIG; Autoimmune

Citation: Vasudhar A (2020) An Unusual Presentation of Guillain -Barre Syndrome: A Case Study. J Neuroinfect Dis 11: 309.

Copyright: © 2020 Vasudhar A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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