Abstract

This collection of articles provides a comprehensive overview of recent advancements in pharmaceutical crystallization. It highlights strategies for engineering crystal properties, including polymorph control, continuous processing, and seeded crystallization. The importance of understanding crystal growth kinetics and the impact of impurities is underscored. Modern approaches integrate Process Analytical Technologies for real-time monitoring and deep learning for process optimization. The research also emphasizes sustainable manufacturing through the use of green solvents, collectively aiming for enhanced product quality, efficiency, and environmental responsibility in API production.