Abstract

This compilation explores the multifaceted regulation of human appetite, a critical determinant of energy balance and body weight. It delves into the complex interplay of hormonal signals, gut microbiota, and neurobiological brain circuits that govern hunger and satiety. The data highlights how lifestyle factors like physical activity, sleep, and stress, along with genetic predispositions, significantly influence appetite. It also examines nutritional strategies, emerging pharmacological interventions for obesity management, and advanced brain imaging techniques that illuminate eating behavior. Understanding these integrated mechanisms is essential for developing effective strategies against obesity and metabolic disorders.