Journal of Obesity & Weight Loss Therapy
Open Access

In the fight against obesity, significant progress has been made in the development of anti-obesity drugs. Currently, six medications are approved by the FDA for long-term obesity treatment. These drugs, when combined with lifestyle modifications, are recommended for individuals with a BMI of 30 or higher or for those with a BMI of 27 or higher with obesity-related comorbidity. Obesity is a global health issue associated with various health risks, including cardiovascular disease, type 2 diabetes, and certain cancers. However, the development of anti-obesity drugs faces limitations. The choice of medication should be personalized, taking into account patient preferences. Additionally, current research focuses on the accumulation of intracellular lipid to further enhance drug development. A comprehensive treatment plan that includes nutrition, physical activity, and behavioral counseling is crucial for long-term success.