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Bacteremia: Profile and Antibiotic Resistance at the Infectious and Tropical Diseases Clinic in Fann Hospital, Dakar, Senegal | OMICS International| Abstract
ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
Open Access

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  • Research Article   
  • J Infect Dis Ther 2017, Vol 6(1): 348
  • DOI: 10.4172/2332-0877.1000348

Bacteremia: Profile and Antibiotic Resistance at the Infectious and Tropical Diseases Clinic in Fann Hospital, Dakar, Senegal

Ndeye Aïssatou Lakhe1*, Khadime Sylla2, Khardiata Diallo Mbaye1, Rahmatoulahi Ndiaye1, Viviane Marie Pierre Cisse Diallo1, Daye KA1, Mouhamadou Lamine Dia3, Louise Fortes Deguenonvo1, Cheikh Tidiane Ndour1 and Moussa Seydi1
1Clinic of Infectious and Tropical Diseases, Fann National University Hospital, , PO: 5035-Fann, Dakar, Senegal
2Parasitology-Mycology Service, Medecine Faculty, Cheikh Anta Diop University, PO: 5005-Fann, Dakar, Senegal
3Bacteriology Laboratories, Fann National University Hospital, , Dakar, Senegal
*Corresponding Author : Ndeye Aïssatou Lakhe, Clinic of Infectious and Tropical Diseases, Fann National University Hospital, PO: 5035-Fann, Dakar, Senegal, Tel: +221 77 541 73 01, Email: [email protected]

Received Date: Jan 12, 2018 / Accepted Date: Jan 25, 2018 / Published Date: Jan 29, 2018

Abstract

The main objective of our study was to perform a situational analysis of bacteremia diagnosed at the Clinic of Infectious Diseases Fann University Hospital in Dakar. This was a retrospective, descriptive study based on the records of patients hospitalized for bacteremia from January 1, 2013 to December 31, 2014. Epidemiological, clinical, biological, therapeutic and evolutionary variables were collected. Data analysis was done using Stata/SE software version 12.1.

Seventy-nine cases of bacteremia were reported in 1922 hospitalized patients at a proportion of 4.1%, and 86 bacterial strains were isolated. The median age was 43 years [IQR: 32; 53]. The main comorbidities found were HIV infection (73%) and high blood pressure (22.2%). Hyperleukocytosis was found in 20 cases (25.32%). The average level of Protein C Reactive was 83.90 ± 56.08 mg/L. Blood culture was monomicrobial in 74 cases (93.7%). The most common isolated bacteria were coagulase-negative staphylococci (23.1%), followed by Pseudomonas aeruginosa/spp (15.1%), Staphylococcus aureus (10.5%), Escherichia coli and Acinetobacter spp (8.1%). Isolated strains had low resistance to Imipenem, Vancomycin and Fusidic Acid. In monotherapy or in combination, the mostly used antibiotic was Ceftriaxone. The average duration of antibiotherapy was 10.40 ± 5.39 days. Thirty-three patients (41.8%) had died.

Cases of bacteremia present a high mortality. Isolated bacterial strains are becoming more resistant to the antibiotics available in our clinic. As a result, the rationalization of their use is adamant.

Keywords: Bacteremia; Antibiotic resistance; Dakar

Citation: Lakhe NA, Sylla K, Mbaye KD, Ndiaye R, Diallo VMPC, et al. (2018) Bacteremia: Profile and Antibiotic Resistance at the Infectious and Tropical Diseases Clinic in Fann Hospital, Dakar, Senegal. J Infect Dis Ther 6: 348. Doi: 10.4172/2332-0877.1000348

Copyright: © 2018 Lakhe NA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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