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Bilateral Internuclear Ophthalmoplegia, Deficiency and High Dose Administration of Vitamin D in Pediatric-Age Multiple Sclerosis: A Pediatric Case Report and Review of the Literature| Abstract

The Neurologist: Clinical & Therapeutics Journal
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  • Case Report   
  • Neurol Clin Therapeut J 2018, Vol 2(1): 1

Bilateral Internuclear Ophthalmoplegia, Deficiency and High Dose Administration of Vitamin D in Pediatric-Age Multiple Sclerosis: A Pediatric Case Report and Review of the Literature

Genç Sel C1*, Altıaylık Ozer P2, Savaş Erdeve S3, Aksoy E1, Dedeoğlu O1 and Oğuz KK4
1Department of Pediatric Neurology, Dr Sami Ulus Pediatric and Training Hospital, , Ankara, Turkey
2Department of Ophthalmology, Ufuk University Faculty of Medicine, , Turkey
3Department Pediatric Endocrinology, Dr Sami Ulus Pediatric and Training Hospital, , Ankara, Turkey
4Department of Radiology, Neuroradiology Section, Hacettepe University of Faculty of Medicine, , Ankara, Turkey
*Corresponding Author : Genç Sel C, Pediatric Neurology Department, Dr Sami Ulus Pediatric and Training Hospital, Babür Street, Altındağ 06080, Ankara, Turkey, Tel: +90 312 305 60 00-63 11, Fax: +90 312 317 03 53, Email: [email protected]

Received Date: Apr 05, 2018 / Accepted Date: Apr 19, 2018 / Published Date: Apr 26, 2018

Abstract

Oculomotor Disorders (OMDs) can be seen as the initial symptoms or during the course of multiple sclerosis (MS). Bilateral internuclear ophthalmoplegia (BINO) is a rare observation as clinical MS onset. BINO and its prognostic value in pediatric-age MS patients are not absolutely known. Vitamin D deficiency is thought to be associated with an increased disease activity in MS and vitamin D is supposed to be a potent immunomodulatory agent. Vitamin D deficiency, its probable effects on the disease pathogenesis, and high dose administration to a pediatric age patient presented with BINO are discussed in this report.

Keywords: Oculomotor disorders; Multiple sclerosis; Bilateral internuclear ophthalmoplegia Vitamin D; Immunomodulatory agent

Citation: Genç Sel C, Altıaylık Ozer P, Savaş Erdeve S, Aksoy E, Dedeoğlu O, et al. (2018) Bilateral Internuclear Ophthalmoplegia, Deficiency and High Dose Administration of Vitamin D in Pediatric-Age Multiple Sclerosis: A Pediatric Case Report and Review of the Literature. Neurol Clin Therapeut J 2: 108.

Copyright: © 2018 Genç Sel C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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