Abstract

Biopolymer-based drug delivery systems have emerged as a promising approach to enhance therapeutic efficacy, improve patient outcomes, and enable targeted treatment in various medical fields. This abstract highlights the research and advancements in biopolymer-based drug delivery systems, focusing on their potential in advancing personalized medicine and targeted therapy. Biopolymers, including proteins, peptides, polysaccharides, and nucleic acids, offer unique properties such as biocompatibility, biodegradability, and tunable physicochemical characteristics. These properties make them ideal candidates for designing drug delivery systems capable of controlled release, prolonged circulation, and targeted delivery to specific tissues or cells. The synthesis and formulation of biopolymerbased drug delivery systems involve techniques such as self-assembly, nanoparticle fabrication, or hydrogel formation. These systems can encapsulate a wide range of therapeutic agents, including small molecules, proteins, nucleic acids, and even gene-based therapies. The design of these systems allows for controlled release kinetics, protecting the drug from degradation and improving its bioavailability. Surface modifications and functionalization of biopolymer-based drug delivery systems enable specific targeting and enhanced cellular uptake. Ligand conjugation, including antibodies, peptides, or aptamers, facilitates selective recognition and binding to target cells or tissues, leading to improved drug delivery and reduced systemic toxicity. The characterization and evaluation of biopolymerbased drug delivery systems encompass physicochemical characterization, drug loading efficiency, release kinetics, cytotoxicity assessment, and in vitro/in vivo studies. These investigations provide valuable insights into the performance, safety, and therapeutic efficacy of the drug delivery systems. This abstract concludes by emphasizing the potential of biopolymer-based drug delivery systems in advancing personalized medicine and targeted therapy. The ability to precisely control drug release, enhance therapeutic efficacy, and minimize off-target effects holds significant promise for improving patient outcomes. The challenges and future prospects for optimizing biopolymerbased drug delivery systems, including scalability, stability, and clinical translation, are also discussed. Continued research and development efforts are essential to fully exploit the potential of biopolymer-based drug delivery systems in personalized medicine and targeted therapy applications. The development and utilization of biopolymerbased drug delivery systems offer innovative strategies for enhancing therapeutic outcomes and advancing the field of drug delivery.