Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar
Causative Factors for the Initiation of Atherosclerotic Plaques | OMICS International| Abstract

Atherosclerosis: Open Access
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Research Article   
  • Atheroscler Open Access 2017, Vol 2(3): 118

Causative Factors for the Initiation of Atherosclerotic Plaques

Gary L Jones*
Institute of Technology, University of Minnesota, Minneapolis, USA
*Corresponding Author : Gary L Jones, Institute of Technology, University of Minnesota, 117 Pleasant St SE, Minneapolis, MN 55455, USA, Email: [email protected]

Received Date: Nov 09, 2017 / Accepted Date: Nov 24, 2017 / Published Date: Nov 30, 2017


Three main factors account for the accumulation of lipoprotein complexes at focal zones of the arterial tree which then can lead to plaque development: (a) diverging flow of the arterial tree which is punctuated at arterial bifurcations, (b) the arterial wall is a semi-permeable membrane with steady bulk flow of fluid, through the interstices of the intimal wall, and (c) shear dependent diffusivity of macromolecules which depends strongly on local shear rate. In the absence of the any factors, either no wall accumulation would occur or lipoproteins would form layers over the entire arterial tree. Models are developed and applied to various zones of an arterial branch, which shows large variations in wall accumulations. The models show that the most important aspects occur from the wall. Very high accumulations of lipids of factors of 2 to 6 times the bulk values in the recirculating flow downstream of branches or at aneurisms while other are show minimal accumulations.
These causative factors directly relate to clinical data, which links smoking to increased wall permeability and thus permeation rate, to incidence and severity of atherosclerotic plaques as well as substantial data linking high blood pressure affecting wall permeation rate with severity or incidence of plaque formation. There is also evidence of feedback whereby the local swelling of the intima increases the interstitial gaps which allow bulk fluid to pass more readily, thus accelerating the local accumulations in these zones.
This work integrates aspects, which have been studied separately but are not all present in previous work.

Keywords: Arteriosclerosis plaques; Smoking; Blood pressure; Diabetes

Citation: Jones GL (2017) Causative Factors for the Initiation of Atherosclerotic Plaques. Atheroscler Open Access 2: 118.

Copyright: ©2017 Jones GL. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Select your language of interest to view the total content in your interested language

Post Your Comment Citation
Share This Article
Article Usage
  • Total views: 3444
  • [From(publication date): 0-2017 - Feb 02, 2023]
  • Breakdown by view type
  • HTML page views: 2891
  • PDF downloads: 553