Clinical Differences between Methicillin-Resistant and -Susceptible Staphylococcus aureus Bacteremia in Adult Patients at a Tertiary Hospital in Japan
Received Date: May 22, 2020 / Accepted Date: Jun 11, 2020 / Published Date: Jun 18, 2020
To determine clinical differences in features of methicillin-susceptible and resistant Staphylococcus aureus (MSSA and MRSA, respectively) bacteremia, 15 adult patients with MRSA bacteremia were compared with 30 adult patients with MSSA bacteremia who were hospitalized during 2015 – 2018.
Compared with MSSA bacteremia patients, MRSA bacteremia patients had a higher age (mean age, 82.0 years and 72.5 years, respectively) and were more likely to have diabetes mellitus significantly (p=0.04). Liver and kidney functions were also significantly decreased in MRSA bacteremia patients compared with MSSA bacteremia patients (p=0.037, p=0.001 and p=0,015, respectively). Moreover, MRSA bacteremia patients showed a much higher mortality rate than MSSA bacteremia patients (60% and 20%, respectively; odds ratio: 2.66, 95% CI; 1.806-4.288, p=0.007).
These data suggest that MRSA bacteremia is more lethal than MSSA bacteremia in adults. Thus, caution should be taken when Staphylococcus aureus is isolated from the blood of patients who are elderly, diabetic, or have liver and kidney dysfunction because MRSA can be more possible pathogens rather than MSSA.
Keywords: Age; Methicillin-resistant Staphylococcus aureus (MRSA); Methicillin-susceptible Staphylococcus aureus (MSSA); Liver dysfunction; Kidney dysfunction
Citation: Watanabe Y, Takano K, Maya H, Kamioka Y, Shimada D, et al. (2020) Clinical Differences between Methicillin-Resistant and - Susceptible Staphylococcus aureus Bacteremia in Adult Patients at a Tertiary Hospital in Japan. J Infect Dis Ther 8: 427.
Copyright: © 2020 Watanabe Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Select your language of interest to view the total content in your interested language
Share This Article
- Total views: 244
- [From(publication date): 0-0 - Oct 22, 2020]
- Breakdown by view type
- HTML page views: 205
- PDF downloads: 39