Clinical Neuropsychology: Open Access
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Case Study   
  • J Neuropsychopharmacol Mental Health 2017, Vol 2(1): 115

Clinical Findings Showing that Non-Convulsive Electric Shock Administration for Patients Receiving Clozapine Therapy for Schizophrenia May Contribute to Stability of Granulocyte Number, the Most Critical Drug Side-Effect

Kotaro Sugita, Yasuhiro Mori, Kousuke Kanemoto and Sotaro Sugita*
Department of Neuropsychiatry, Aichi Medical University, Nagakute- shi, Japan
*Corresponding Author : Sotaro Sugita, Department of Neuropsychiatry, Aichi Medical University, P.O. 480-1195, Yazako Karimata, 1–1, Nagakute-shi, Aichi Prefecture, Japan, Tel: + 81561623311, Email: Shallonsugita@gmail.com

Received Date: Jan 09, 2017 / Accepted Date: Feb 11, 2017 / Published Date: Feb 20, 2017

Abstract

Two treatment-resistant schizophrenic patients were administered clozapine, but showed a decrease in granulocytes. As an alternative treatment, we administered non-convulsive Electric Shock Therapy (ECT) (modified- ECT: m-ECT) to both and the number of granulocytes increased to a level considered safe for clozapine ingestion. Then, under continuation of m-ECT, we gradually increased the dose of the drug. After 10-14 m-ECT sessions in both patients, the number of granulocytes became stable at approximately 5000/mm3 and m-ECT was completed. Our findings show the possibility of treatment for therapy-resistant patients who are unable to receive clozapine because of reduced granulocyte number.

Keywords: Clozapine therapy; Electric shock; Schizophrenia; Granulocytes

Citation: Sugita K, Mori Y, Kanemoto K, Sugita S (2017) Clinical Findings Showing That Non-Convulsive Electric Shock Administration for Patients Receiving Clozapine Therapy for Schizophrenia May Contribute to Stability of Granulocyte Number, the Most Critical Drug Side-Effect. J Neuropsychopharmacol Mental Health 2: 115.

Copyright: © 2017 Sugita K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any Smedium, provided the original author and source are credited.

Top