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Effect of Carvacrol Tested on Different <em>in vivo</em> and <em>in vitro</em> Experimental Studies: Systematic Review | OMICS International| Abstract
ISSN: 2167-065X

Clinical Pharmacology & Biopharmaceutics
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  • Review Article   
  • Clin Pharmacol Biopharm 2018, Vol 7(1): 181
  • DOI: 10.4172/2167-065X.1000181

Effect of Carvacrol Tested on Different in vivo and in vitro Experimental Studies: Systematic Review

Andressa Coelho Ferreira1, Cristiano Teixeira Mostarda1,2,3, Carlos José Dias1,3*, Louryval Coelho Paixao3, Flavio De Oliveira Pires1,3, Emydia Rosa Do Rego Barros Pires Leal4 and Marcelo Souza De Andrade5
1Department of Cardiovascular Adapatations to Exercise, Universidade Federal do Maranhão, , São Luis-MA, Brazil
2Department of Educação Física, Universidade Federal do Maranhão, , São Luis-MA, Brazil
3Department of Biotecnologia-RENORBIO, Universidade Federal do Maranhão, , São Luis-MA, Brazil
4Department of Ciências Biológicas e Saúde, Departamento de Biologia, Universidade Federal do Maranhão, , São Luis-MA, Brazil
5Department of Ciências Biológicas e Saúde, Departamento de Ciências Fisiológicas, Universidade Federal do Maranhão, , São Luis-MA, Brazil
*Corresponding Author : Carlos José Dias, Department of Cardiovascular Adapatations to Exercise, Universidade Federal do Maranhão, São Luis-MA, Brazil, Tel: 65085-580, Email: [email protected]

Received Date: Feb 12, 2018 / Accepted Date: Feb 21, 2018 / Published Date: Feb 23, 2018

Abstract

The objective of the study was to show carvacrol isolad in in vitro and in vivo assays to verify the effects of their dosages on different application areas. The searches were realized in the following databases, pubmed, and academic google using the descriptors carvacrol; carvacrol and in vitro; carvacrol and in vivo. Thus that in academic google we still use in the advanced search, exclusion of patents and references, as well the inclusion the articles that had the descriptors present in the title. For eligibility, there were 13 articles for analysis. In which, the carvacrol proved to be effective with antimicrobial action, anti-carcinogenic, immune system cell protector, reducer of gastrointestinal lesions, optimizer anti-carcinogenic drug in nanoparticles, as well as mitotic index reducer in bone marrow cells used in high dosages. In conclusion, it is understood that the dosage applied in the right amount can be efficient in the cancer control and elimination of bacteria, in which the carvacrol acts as promising herbal remedy for clinical use.

Keywords: Carvacrol; Dosage; Systematic review

Citation: Ferreira AC, Mostarda CT, Dias CJ, Paixao LC, Pires FDO, et al. (2018) Effect of Carvacrol Tested on Different in vivo and in vitro Experimental Studies: Systematic Review. Clin Pharmacol Biopharm 7: 181. Doi: 10.4172/2167-065X.1000181

Copyright: ©2018 Ferreira AC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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