Effect of N3-Poliunsaturated Fatty Acids as Coadjuvant in the Antihypertensive Treatment in Spanish Postmenopausal Women
Received Date: Aug 23, 2017 / Accepted Date: Sep 04, 2017 / Published Date: Sep 11, 2017
Objective: The purpose of this study is to evaluate the effects of taking low doses of omega-3 (1,5 g/day) in hypertensive women.
Method: Longitudinal clinical trial Health Center of San Fernando de Badajoz. Primary care. 55 postmenopausal hypertensive women. For the study, participants were divided into two groups, group supplementation (GS) (n=28) and one control group (CG) (n=27). Supplementation with n-3 PUFA to the experimental group for 6 months (1.5 g/day). The control group was given nothing. The variables of the study have been blood pressure, n-3 fatty acid supplementation and it was tried to control nutritional intake.
Results: In SG, systolic blood pressure decreased significantly at the third (p<0.001) and sixth (p<0.001) month after starting the study, and three months (p<0.01) since the end of supplementation. With regards to diastolic blood pressure levels in the same group, also produced a decrease that became significant (p<0.01) after six months of supplementation and maintained at three months of concluding the supplementation, even without acquire statistically signification. We have shown increases in the plasma percentages of fatty acids C20:5n3 and C22:6n3, after three months of initiating supplementation (p<0.05), after 6 months of it (p<0.001) and in three months of leaving supplementation (p<0.001). Arachidonic acid decreases throughout the supplementation period and this reached a statistically significant difference after 6 months within supplementation.
Conclusions: The intake of 1.5 g/day of fish oil as coadjuvant in the treatment of all kinds of arterial hypertension improves blood presure and other cardiovascular diseases.
Keywords: Postmenopausic women; Hypertension; Lipids; n-3-fatty acid
Citation: Muñoz D, Maynar I, Maynar MA, Bartolomé I, Maynar IS, et al. (2017) Effect of N3-Poliunsaturated Fatty Acids as Coadjuvant in the Antihypertensive Treatment in Spanish Postmenopausal Women. Sports Nutr Ther 2: 127. Doi: 10.4172/2473-6449.1000127
Copyright: © 2017 Muñoz D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.