alexa Effect of Rose Hip Extract on Spatial Memory in Rats and Correlation with Hippocampal Expression of Phosphorylated Protein Kinase C | OMICS International| Abstract
ISSN: 2167-065X

Clinical Pharmacology & Biopharmaceutics
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  • Research Article   
  • Clin Pharmacol Biopharm 2020, Vol 9(3): 200

Effect of Rose Hip Extract on Spatial Memory in Rats and Correlation with Hippocampal Expression of Phosphorylated Protein Kinase C

Khushboo Mittal*
Department of Pharmacology, Advanced Institute of Pharmacy, Delhi, India
*Corresponding Author : Khushboo Mittal, Department of Pharmacology, Advanced Institute of Pharmacy, Delhi, India, Tel: +917417527424, Email: [email protected]

Received Date: Apr 29, 2020 / Accepted Date: Jul 20, 2020 / Published Date: Jul 27, 2020

Abstract

Search for newer plant derived medicinal is always on. Rose hip plant is the plant showing promising potential. Reverse pharmacology and transdisciplinary exploratory studies on rose hip are increasingly being studied these days. In this study seven group of animals were assessed with different dose levels were assessed for their effects on spatial memory by using Morris water maze and radial arm maze. A significant increase in TSTQ and decrease in escape latency time was observed in test groups as compared to memory impaired and control group. Also significant increased expression of protein kinase C was observed in test groups as compared to memory impaired group.

Keywords: Spatial memory; Radial arm maze; Morris water maze; Hippocampus; Reverse transcriptase polymerase chain reaction

Citation: Mittal K (2020) Effect of Rose Hip Extract on Spatial Memory in Rats and Correlation with Hippocampal Expression of Phosphorylated Protein Kinase C. Clin Pharmacol Biopharm 9: 200.

Copyright: © 2020 Mittal K. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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