Effect of Rose Hip Extract on Spatial Memory in Rats and Correlation with Hippocampal Expression of Phosphorylated Protein Kinase C
Received Date: Apr 29, 2020 / Accepted Date: Jul 20, 2020 / Published Date: Jul 27, 2020
Abstract
Search for newer plant derived medicinal is always on. Rose hip plant is the plant showing promising potential. Reverse pharmacology and transdisciplinary exploratory studies on rose hip are increasingly being studied these days. In this study seven group of animals were assessed with different dose levels were assessed for their effects on spatial memory by using Morris water maze and radial arm maze. A significant increase in TSTQ and decrease in escape latency time was observed in test groups as compared to memory impaired and control group. Also significant increased expression of protein kinase C was observed in test groups as compared to memory impaired group.
Keywords: Spatial memory; Radial arm maze; Morris water maze; Hippocampus; Reverse transcriptase polymerase chain reaction
Citation: Mittal K (2020) Effect of Rose Hip Extract on Spatial Memory in Rats and Correlation with Hippocampal Expression of Phosphorylated Protein Kinase C. Clin Pharmacol Biopharm 9: 200. Doi: 10.4172/2167-065X.1000200
Copyright: © 2020 Mittal K. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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