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ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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  • J Infect Dis Ther 2017, Vol 5(6): 345
  • DOI: 10.4172/2332-0877.1000345

Helicobacter Pylori Infection Induces Gastric Cancer and the Cancer/Testis Antigens Expression

Nobue Futawatari1#, Takashi Fukuyama2*#, Rui Yamamura2 and Noritada Kobayash2
1Department of Surgery, school of Medicine, Kitasato University, Sagamihara, Kanagawa, Japan
2Division of Biomedical Research, Kitasato University Medical Center, Kitamoto, Saitama, Japan
#Contributed equally to this work
*Corresponding Author : Takashi Fukuyama, Division of Biomedical Research, Kitasato University Medical Center, 6-100 Arai, Kitamoto, Saitama 364-8501, Japan, Tel: +81-48-593-1236, Fax: +81-48-593-1262, Email: [email protected]

Received Date: Dec 08, 2017 / Accepted Date: Dec 12, 2017 / Published Date: Dec 15, 2017

Abstract

Helicobacter pylori (HP) are known to induce gastritis, atrophy, intestinal metaplasia, dysplasia, and stomach malignancy. HP infection also induces cancer/testis antigens (CTAs) during or after gastric malignancy. This study aims to elucidate the relationship between HP and CTAs, especially melanoma antigen-A3 and Kitakyushu lung cancer antigen-1.

Keywords: Helicobacter pylori; Gastric cancer; Tumor antigen; Cancer/testis antigen; KK-LC-1; MAGE

Citation: Futawatari N, Fukuyama T, Yamamura R, Kobayashi N (2017) Helicobacter Pylori Infection Induces Gastric Cancer and the Cancer/Testis Antigens Expression. J Infect Dis Ther 5: 345. Doi: 10.4172/2332-0877.1000345

Copyright: © 2017 Futuwatari N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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