Evaluating the Photosensitivity of the Chinese Chlorella on Red Blood Cells
Received Date: May 28, 2014 / Accepted Date: Jun 04, 2014 / Published Date: Jun 07, 2014
Abstract
The photosensitivity of the Chinese Chlorella (CC) which is a natural algae is investigated by considering its ability of killing red blood cells when their mixture exposed to light. Different experimental studies were performed to figure out the photohemolysis rate of red blood cells mixed with different concentrations of the Chinese Chlorella at different temperatures and irradiation times. Photohemolysis curves are obtained using different approaches: the continuous and delayed irradiations. All obtained data were fitted to the Gompartz function and results showed that the photohemolysis rate increases as the temperature as well as the concentration of the Chinese Chlorella increases. In general, Chinese Chlorella represents a good candidate for a photosensitive material that can be used in photodynamic therapy.
Keywords: Photosensitivity; Photohemolysis; Chinese Chlorella; photodynamic therapy
Citation: Alzoubi FY, AL-Akhras MA, Al-Omari HA, Aljarrh K (2014) Evaluating the Photosensitivity of the Chinese Chlorella on Red Blood Cells. J Mol Pharm Org Process Res 2: 114. Doi: 10.4172/2329-9053.1000114
Copyright: ©2014 Alzoubi FY, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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