alexa Evaluating the Photosensitivity of the Chinese Chlorella on Red Blood Cells | OMICS International| Abstract

ISSN: 2329-9053

Journal of Molecular Pharmaceutics & Organic Process Research

  • Research Article   
  • J Mol Pharm Org Process Res 2014, Vol 2(2): 114
  • DOI: 10.4172/2329-9053.1000114

Evaluating the Photosensitivity of the Chinese Chlorella on Red Blood Cells

Fedda Y Alzoubi1, M-Ali AL-Akhras1*, Hesham A Al-Omari1 and Khaled Aljarrh1,2
1Department of Physics, Bio-Medical Physics Laboratory, Jordan University of Science and Technology, Jordan
2College of Applied Medical Science, King Saud bin Abdulaziz University for Health Sciences, Al-Ahsa, Saudi Arabia
*Corresponding Author : M-Ali AL-Akhras, Department of Physics, Bio-Medical Physics Laboratory, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan, Tel: +96227201000, Fax: +962-2-7201071, Email: [email protected]

Received Date: May 28, 2014 / Accepted Date: Jun 04, 2014 / Published Date: Jun 07, 2014

Abstract

The photosensitivity of the Chinese Chlorella (CC) which is a natural algae is investigated by considering its ability of killing red blood cells when their mixture exposed to light. Different experimental studies were performed to figure out the photohemolysis rate of red blood cells mixed with different concentrations of the Chinese Chlorella at different temperatures and irradiation times. Photohemolysis curves are obtained using different approaches: the continuous and delayed irradiations. All obtained data were fitted to the Gompartz function and results showed that the photohemolysis rate increases as the temperature as well as the concentration of the Chinese Chlorella increases. In general, Chinese Chlorella represents a good candidate for a photosensitive material that can be used in photodynamic therapy.

Keywords: Photosensitivity; Photohemolysis; Chinese Chlorella; photodynamic therapy

Citation: Alzoubi FY, AL-Akhras MA, Al-Omari HA, Aljarrh K (2014) Evaluating the Photosensitivity of the Chinese Chlorella on Red Blood Cells. J Mol Pharm Org Process Res 2: 114. Doi: 10.4172/2329-9053.1000114

Copyright: ©2014 Alzoubi FY, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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