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Evaluation of Platelet Parameters as Prognostic Analysis in Cardiac Intensive Care Unit Patients | OMICS International| Abstract

Atherosclerosis: Open Access
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  • Research Article   
  • Atheroscler Open Access 2017, Vol 2(1): 106

Evaluation of Platelet Parameters as Prognostic Analysis in Cardiac Intensive Care Unit Patients

Jose Gildo De Moura Monteiro Júnior1*, Dilênia De Oliveira Cipriano Torres2, Maria Cleide Freire Clementino Da Silva2, Ana Célia Oliveira Dos Santos3, Rebeca Mangabeira Correia4, Thiago Gadelha Batista Dos Santos4, Thaisa Freitas De Oliveira4, Isany Acioly Texeira Mesquita5 and Dário Celestino Sobral Filho6
1Coronary Care Unit of PROCAPE (Pernambuco Cardiac Emergency Hospital), University of Pernambuco, , Recife, Pernambuco, Brazil
2Laboratory of Clinical Analyses at, The University of Pernambuco, Brazil
3Institute of Biological Sciences, The University of Pernambuco, Brazil
4Academic at The Medical School, The University of Pernambuco, Brazil
5Post-Graduation in Hematology, The University of Pernambuco, Brazil
6Medical School, The University of Pernambuco, Brazil
*Corresponding Author : Jose Gildo De Moura Monteiro Júnior, Pronto Socorro Cardiológico de Pernambuco (PROCAPE) Unidade Coronária -1º andar Rua dos Palmares, S/N, Santo Amaro 50.100-060 Recife, PE –, Brazil, Tel: (81)31817188, Email: [email protected]

Received Date: Jan 11, 2017 / Accepted Date: Mar 06, 2017 / Published Date: Mar 12, 2017

Abstract

Objective: Platelet activation and consumption are common in critically ill patients and are associated with poorer prognosis. Inflammatory and thrombotic conditions may alter platelet size, which can be detected on routine blood cell analysis by evaluation of mean platelet volume. The aim of the present study was to investigate the evaluation of platelet parameters as a predictor of all-cause mortality in cardiac intensive care unit (ICU) patients. Methods: Platelet count and mean platelet volume were measured daily in cardiac ICU and were classified in three categories of thrombocytopenia, according to the average value of platelet count during hospitalization: mild (100-149 X 109/L), moderate (50-99 X 109/L) and severe (hematological disease, who have had previous use of steroids or chemotherapy, those that were readmitted after hospital discharge and patients who died in the first 24 hrs after admission. A correlation analysis was performed to identify independent predictors of mortality. Results: We included 165 patients (61 ± 16 years, 55.8% male, average length of stay in ICU was 10 ± 10 days). In total, 42 (25.4%) out of the 165 patients showed platelet count

Keywords: Cardiac intensive care unit; Daily platelet parameters; Mean platelet volume (MPV); Platelet count; Sequential organ failure assessment (SOFA); Acute physiology and chronic health evaluation II (APACHE II); Mortality

Citation: Júnior JG de MM, Torres D de OC, Silva MCFC da, Santos ACO dos, Correia RM, et al. (2017) Evaluation of Platelet Parameters as Prognostic Analysis in Cardiac Intensive Care Unit Patients. Atheroscler open access 2: 106.

Copyright: © 2017 Junior JG de MM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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