Abstract

Advanced cancer patients gradually experience deterioration of their physical condition and symptoms. Prognostic information is quite important for patients, their caregivers and medical staff. The Glasgow Prognostic Score (GPS)/modified GPS (mGPS) is one of the objective prognostic indicators. This study aimed to review the prevalence of GPS/mGPS and its impact on the prognostic value, physical function, quality of life and symptoms, and cancer cachexia among cancer patients who had received supportive care without plan of any anti-tumor therapy. Six studies were identified. The increase in GPS/mGPS score was correlated with poor prognosis, poor performance status and weight loss in patients without anti-tumor therapy. However, no evidence about the correlation between GPS/mGPS and activities of daily living, quality of life and symptoms existed. More detailed classification of GPS/mGPS will be needed to adequately reflect the general conditions of advanced cancer patients who have received supportive care without plan of any anti-tumor therapy.

Keywords: Glasgow Prognostic Score; Palliative Care; Cancer; Prognostic Indicator