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Impact on Breast Cancer Mortality of Breast Cancer Screening in Case- Control Studies | OMICS International| Abstract
ISSN: 2381-8727

International Journal of Inflammation, Cancer and Integrative Therapy
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Impact on Breast Cancer Mortality of Breast Cancer Screening in Case- Control Studies

Marcas Pape*
Department of Epidemiology, Biostatistics and HTA, Netherlands
*Corresponding Author : Marcas Pape, Department of Epidemiology, Biostatistics and HTA, Netherlands, Email:

Received Date: May 29, 2023 / Published Date: Jun 29, 2023


Background: Different levels of breast cancer mortality reduction have been shown in recent case-control studies on the efficacy of population-based breast cancer screening. We looked into how the case-control research design's elements, such as the definition of cases and exposure to screening, affected these discrepancies.

Materials and procedures: We looked at six case-control studies that were carried out in South Australia, The Netherlands, Wales, Iceland, central and northern Italy, and East Anglia (UK).

Results: The difference between screened and unscreened women's breast cancer mortality decreased from 38% to 70% in several case-control studies. We observed design changes, such as whether to include or exclude the first years of screening and the self-selection bias correction factor.

Conclusions: The case-control studies' designs were generally comparable. It is highly improbable that changes in the case-control study design are to blame for the variances in the amount of breast cancer mortality reductions. These variations must be the result of additional elements, such as how the service screening programme is set up and the attendance rate. These case-control studies' estimated decrease in breast cancer mortality suggests that the impact of contemporary mammographic screening is at least consistent with the benefit noted by the previous
randomised screening trials.

Citation: Pape M (2023) Impact on Breast Cancer Mortality of Breast CancerScreening in Case-Control Studies. Int J Inflam Cancer Integr Ther, 10: 221.

Copyright: © 2023 Pape M. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.