Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar
Insulin Resistance Improves More in Women than In Men in Association with a Weight Loss Intervention | OMICS International| Abstract
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Research Article   
  • J Obes Weight Loss Ther 8:365,
  • DOI: 10.4172/2165-7904.1000365

Insulin Resistance Improves More in Women than In Men in Association with a Weight Loss Intervention

Badri NW, Flatt SW, Barkai HS, Pakiz B, Heath DD and Rock CL*
Department of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA, USA
*Corresponding Author : Rock CL, PhD, RD, University of California, San Diego, 3855 Health Sciences Drive, Room 3077, La Jolla, CA 92093-0901, USA, Tel: +1 858 822 1126, Email: [email protected]

Received Date: Jan 24, 2018 / Accepted Date: Jan 29, 2018 / Published Date: Feb 05, 2018


Background: Fasting glucose and homeostatic model assessment-insulin resistance (HOMA-IR) are important measures of the risk for metabolic syndrome and diabetes. Weight loss interventions are considered part of the first line of therapy for those who develop disease states associated with insulin resistance, such as pre-diabetes, diabetes, or metabolic syndrome. Sex differences in insulin resistance have been extensively reported, but sex differences in the ability to improve insulin sensitivity are not well-established. This study sought to identify factors that predict change in HOMA-IR in response to weight loss.
Methods: Non-diabetic subjects who were overweight/obese (n=100) were randomly assigned to a walnutenriched reduced-energy diet or a standard reduced-energy-density diet in a 6-month weight loss intervention. There were no significant differences in weight change, glucose, insulin, or HOMA-IR between the two diet groups. These subjects were combined into a single cohort and analyzed with multivariate analysis.
Results: The combined groups lost an average of 8.7 kg (p<0.0001), decreased serum glucose by an average 0.2 mmol/L (p<0.001), and decreased HOMA-IR by an average of 1.4 (p<0.0001). Change in HOMA-IR (R2=0.69) was positively associated with weight change (p<0.0001) and male sex (p<0.01), and negatively associated with baseline HOMA-IR (p<0.0001).
Conclusion: Findings from this study suggest that men may have a more difficult time improving insulin sensitivity as compared with women with an equivalent weight loss and baseline HOMA-IR. One hypothesis to explain the differences across sexes may be due to sex differences in visceral adipose fat (VAT). This may mean that insulin resistant men require more aggressive intervention than women to prevent progression to metabolic syndrome or diabetes.

Keywords: Walnuts; Insulin resistance; Weight loss; Diabetes; Metabolic syndrome; Sex

Citation: Badri NW, Flatt SW, Barkai HS, Pakiz B, Heath DD et al. (2018) Insulin Resistance Improves More in Women than In Men in Association with a Weight Loss Intervention. J Obes Weight Loss Ther 8: 365. Doi: 10.4172/2165-7904.1000365

Copyright: © 2018 Badri NW, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.