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Isolated Splenic Metastasis in a Patient with Lung Carcinoma: Case Report and Review of the Literature | OMICS International| Abstract
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
Open Access

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  • Case Report   
  • J Clin Exp Pathol 2015, Vol 5(6): 252
  • DOI: 10.4172/2161-0681.1000252

Isolated Splenic Metastasis in a Patient with Lung Carcinoma: Case Report and Review of the Literature

Qi Cai* and Peter Kragel
Department of Pathology, BrodySchool of Medicine, East Carolina University, USA
*Corresponding Author : Qi Cai, Department of Pathology, Brody School of Medicine, East Carolina University, Greenville, NC, USA, Tel: 0012528478789, Fax: 0012527448200, Email: [email protected]

Received Date: Aug 25, 2015 / Accepted Date: Sep 17, 2015 / Published Date: Sep 20, 2015

Abstract

The prevalence of metastasis to the spleen is low in cancer patients. Splenic metastasis usually occurs only at the terminal stages of disease progression and is associated with multiple metastases in other sites. Only 19 cases of isolated splenic metastasis in patients with primary lung cancer have been reported in the literature. We report a case of isolated splenic metastasis in a patient with adenocarcinoma of the lung identified by CT scan and confirmed by pathologic examination and immunohistochemistry. Follow up positron emission tomography (PET) scan also identified sacral metastasis. The use of advanced imaging modalities such as PET scan may identify additional metastatic foci in patients who were previously considered to have isolated splenic metastasis.

Keywords: Lung adenocarcinoma; Isolated splenic metastasis; Positron emission tomography; Thyroid transcription factor-1

Citation: Cai Q, Kragel P (2015) Isolated Splenic Metastasis in a Patient with Lung Carcinoma: Case Report and Review of the Literature. J Clin Exp Pathol 5:252. Doi: 10.4172/2161-0681.1000252

Copyright: © 2015 Cai Q et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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