Abstract

Dementia, a neurodegenerative disorder marked by cognitive decline, poses a significant challenge to global healthcare systems. Traditional therapeutic approaches primarily focus on managing symptoms, with limited efficacy in halting or reversing the disease’s progression. Ayurvedic Rasayana therapy, which is aimed at rejuvenation and revitalization, has garnered attention for its potential neuroprotective effects in the management of neurodegenerative diseases such as dementia. Rasayanas are believed to possess antioxidant, anti-inflammatory, and neuroprotective properties, which may help in improving cognitive function and delaying neurodegeneration. This article reviews the existing research on the neuroprotective effects of Ayurvedic Rasayanas in various dementia models, including Alzheimer's disease and other neurodegenerative conditions. The findings suggest that Rasayana compounds may hold promise in mitigating the symptoms and progression of dementia through multiple pathways. However, more rigorous clinical trials and mechanistic studies are necessary to confirm their therapeutic potential.