Abstract

Obesity and various sleep disorders, notably obstructive sleep apnea (OSA), share intricate bidirectional links. Obesity contributes to OSA through anatomical and physiological changes, while OSA exacerbates metabolic dysfunction. Sleep deprivation and irregular sleep durations are crucial drivers of weight gain, impacting appetite-regulating hormones and inflammation. Other disorders like central sleep apnea (CSA) and restless legs syndrome (RLS) also associate with obesity. Interventions range from bariatric surgery and lifestyle modifications to considering genetic and epigenetic influences. Recognizing these complex relationships is key for comprehensive patient management, improving sleep quality, and addressing long-term health risks