Immunology: Current Research
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  • Research Article   
  • Immunol Curr Res,

On the Link between Ellagic Acid and the Immune Balance between Human Mononuclear and Colon Carcinoma Cells

Hanna Bessler1,2* and Meir Djaldetti1,2
1Laboratory for Immunology and Hematology Research, Rabin Medical Center, Hasharon Hospital, , Petah Tiqva, Israel
2Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel
*Corresponding Author : Hanna Bessler, Laboratory for Immunology and Hematology Research, Rabin Medical Center, Hasharon Hospital, 7, Keren Kayemet St, Petah Tiqva, Israel, Tel: 972-3-9372480, Fax: 972-3-9372388, Email: hannab@clalit.org.il

Received Date: Oct 29, 2017 / Accepted Date: Nov 12, 2017 / Published Date: Nov 19, 2017

Abstract

Pomegranate and particularly its phenolic compound ellagic acid (EA) have been well renowned as a therapeutic remedy for a long list of illnesses including inflammation and cancer. The beneficial activity of EA has been attributed to a number of factors comprising its immunomodulatory effect. Our aim was to examine the effect of EA on the immune relationship between human peripheral blood mononuclear cells (PBMC) and colon cancer cells from two human colon carcinoma cell lines.

Keywords: Mononuclear cells; Cancer cells; Interleukins; Cross-talk

Citation: Bessler H, Djaldetti M (2017) On the Link Between Ellagic Acid and the Immune Balance Between Human Mononuclear and Colon Carcinoma Cells. Immunol Curr Res 1: 101.

Copyright: © 2017 Bessler H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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