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Immunology: Current Research is a budding journal, having colossal potential and possibilities in exploring the immunological aspects related to health and disease. All types of research articles related to immune system are cordially appreciated for the inaugural issue of the journal. In brief, the journal is a monthly, peer-reviewed, open access journal. We believe, information in research ground should be free from any bondage and that’s why we encourage open access policy for all the communications. In the initial stages of the journal, we expect timely articles for global reach, which can make a big contribution towards the progress of science.
The scope of the ‘Immunology: Current Research’ will cover the major aspects of the immune system related issues like intravesical immunotherapy, microbial immunology, clinical immunology, cellular immunology, translational immunology, transplantation immunology, neuroinflammatory disorders, tumor immunology, vaccine immunology, inflammatory disorders, ocular immunology and inflammation. Quality and standard of the journal is the biggest concern to provide a world-class platform for the communication with novel concepts. Most of our endeavors are focused to maintain this agenda with strict and fixed vision. Moreover, we consider the value of facts and ethics in the research and hence, all the articles submitted for publication will be evaluated through stringent guideline of fact checkup and ethical clearance. Accuracy and authenticity in data representation is advised regardless the article types under communication.
We appreciate the original contribution from the authors. However, selection procedure will go through strict peer-review procedure according to the norms of the organization. The submitted manuscript will be selected for publication only if the reviewer suggests positive comments for the article. Besides the reviewer’s comment, dependency of final decision will be fostered by our esteemed editorial board members, who are experienced and expert in the said field of study. We emphasize on the fast processing of the manuscript, in doing so, section editors and guest editors will be playing critical role for the communicated articles. Immunology Current Research journal is heartening researchers to submit relevant research works within the scope of the journal. Author may submit their manuscripts through the journal's online submission as an e-mail attachment at - [email protected]
vaccination: A vaccination is the injection of a killed or weakened organism that produces immunity in the body against that organism.Vaccinations began in the 18th century with the work of Edward Jenner and the smallpox vaccine. This is the most effective method of preventing infectious diseases widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the elimination of diseases such as polio, measles, and tetanus from much of the world.
Complement system: it is part of the immune system that helps, or “complements” the ability of antibodies to clear pathogens or mark them for destruction by other cells. There are different complement systems like: Classical, alternative, Lectin
• Classical: starts when antibody bind to bacteria
• Alternative: starts "spontaneously"
• Lectin: starts when lectins bind to mannose on bacteria
Clinical Immunology: it is study of diseases caused by disorders of the immune system. In clinical immunology immune reactions play a part in the pathology and clinical features. Clinical immunologists also study ways to prevent the immune system's attempts to destroy transplant rejection. The diseases caused by disorders of the immune system are following:
Immunodeficiency: The part of immune system fails to provide an adequate response like chronic granulomatous disease and primary immune diseases.
Autoimmunity: in autoimmunity it attacks own host’s body like rheumatoid arthritis, Hashimoto's disease.
Radiotherapy: Radiotherapy uses high-energy rays to treat disease. It can be given both externally and internally.by external radiotherapy high- energy X-rays at the affected area using a large machine, and by internal radiotherapy material placed inside the body. Radiotherapy is generally considered the most effective cancer treatment after surgery, but how well it works varies from person to person.The response of a cancer to radiation is described by its radiosensitivity. Highly radiosensitive cancer cells killed by moderate doses of radiation. It include leukemias, lymphomas and germ cell tumors. Radiation therapy is used to treat early stage Dupuytren's disease and Ledderhose disease.This techniques is used in non-cancerous diseases. It works by damaging the DNA of cancerous cells.
Antibody, also known as an immunoglobulin. It is Y-shaped proteins that are produced by the immune system to help stop intruders from harming the body. When an intruder enters the body, the immune system springs into action. These invaders Like antigens, viruses, bacteria, or other chemicals. it is divided into five primary classes.
· IgA (immunoglobin A)
· IgD (immunoglobin D)
· IgE (immunoglobin E)
· IgG (immunoglobin G)
· IgM (immunoglobin M)
Antigen: it is a toxin or foreign substance which induces an immune response in the body, especially the production of antibodies. Antigens are substances (usually proteins) on the surface of cells, viruses, fungi, or bacteria. Nonliving substances such as toxins, chemicals, drugs, and foreign particles can also be antigens. The immune system recognizes and destroys, or tries to destroy, substances that contain antigens. There are three types of antigens present in our body: macrophages, dendritic cells and В cells. The antigen and antibody Interaction is called specific chemical interaction. It produced by white blood cells and antigens during immune reaction.
Immunotherapy: it is the treatment of disease by inducing, enhancing, or repressing an immune response. Immunotherapies are fundamentally the way we treat cancer.These promising and potent drugs aim to tackle the body’s immune system, directing it to attack tumors. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural killer cells (NK Cell), cytotoxic T lymphocytes (CTL).These immune effector helps in fight against cancer by targeting abnormal antigens which expressed on tumor cells.
Hypersensitivity: it is a abnormal immune reactions produced by the normal immune system like allergy, autoimmunity. It include autoimmune disease, in this disease result from uncontrolled response of foreign antigens and mainly chronic problems occur. hypersensitivity diseases classified into following groups.
• Immediate (type I) hypersensitivity
• Antibody-mediated (type II) hypersensitivity
• Immune complex disease
• cell-mediated immune memory response
• Autoimmune disease
Baculovirus: Baculovirus is a family of viruses. Arthropods, lepidoptera, hymenoptera, diptera, and decapoda serve as natural hosts. The baculoviruses used as biological control agents are in the genus Nucleopolyhedrovirus, so "baculovirus" or "virus" will hereafter refer to nucleopolyhedroviruses. These viruses have no negative impacts on plants, mammals, birds, fish, or even on non-target insects. Baculovirus expression in insect cells represents a robust method for producing recombinant glycoproteins or membrane proteins. It produced proteins are currently under study as therapeutic cancer vaccines. It is considered a safe option for use in research applications.
Allergy: Allergy is the condition caused by immune system reacts abnormally to a foreign substance. It is also knowns as allergic diseases, various types. Drug allergy, Food allergies, Allergic asthma, Seasonal allergies, Animal allergy.
Related Journals: Journal of Allergy & Therapy, The Journal of Allergy and Clinical Immunology: In Practice, Allergy/Immunology Journals, Journal of Allergy and Clinical Immunology,Clinical Reviews in Allergy and Immunology,Current Opinion in Allergy and Clinical Immunology.
Immunodeficiency: disorders prevent our body from fighting infections and diseases. This type of disorder like viruses and bacterial infections. It classified into primary immunodeficiency. The following diseases and conditions are linked to primary and secondary immunodeficiency disorders: ataxia-telangiectasia, Chediak-Higashi syndrome, combined immunodeficiency disease,complement deficiencies, DiGeorge syndrome.
Related journals of Immunodeficiency
Journal of Acquired Immune Deficiency Syndromes, Rheumatology: Current Research, Journal of Vaccines & Vaccination, Journal of Roentgenology ,Journal of Primary & Acquired Immunodeficiency Research.