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Post-partum Lymphocytic Hypophysitis in Ethiopian Woman's | OMICS International| Abstract

Journal of Obesity and Metabolism
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  • Review Article   
  • J Obes Metab 2022, Vol 5(1): 110
  • DOI: 10.4172/jomb.1000110

Post-partum Lymphocytic Hypophysitis in Ethiopian Woman's

Amare Gulilat Mamo1*, Getahun Tarekegn1, Abebe Mekonnen2 and Tewodros Endale3
1Consultant Internist and Endocrinologist, Department of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
2Neuroradiologist, Department of Radiology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
3Radiologist, Department of Radiology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
*Corresponding Author : Amare Gulilat Mamo, Consultant Internist and Endocrinologist, Department of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia, Email: amare_gulilat@yahoo.com

Received Date: Oct 24, 2020 / Accepted Date: Feb 22, 2022 / Published Date: Feb 23, 2022

Abstract

A 28 year-old young woman who was referred from Bahir Dar, Ethiopia for possible neurosurgical evaluation and management after she presented with headache and failure to lactate one month following delivery. The initial hormonal analysis was consistent with hypopituitarism. The magnetic resonance imaging (MRI) of the Brain done initially showed diffuse enlargement of the pituitary gland and thickening of the pituitary stalk. Most of the pituitary axes recovered after one month of hormonal replacement therapy. The follow-up MRI done after four weeks showed resolution of pituitary gland enlargement and stalk thickening. Based on clinical presentation, pituitary hormonal insufficiency and Brain MRI findings, the diagnosis of lymphocytic hypophysitis was made. Lymphocytic hypophysitis is a rare disease in which inflammation of the pituitary gland and stalk occurs. It is associated with transient or permanent insufficiency pituitary hormones. It usually occurs in women during third trimester of pregnancy or postpartum period. Systemic corticosteroid treatment at early stage may avoid unnecessary surgery in some cases but there are reported cases of spontaneous resolution.

Citation: Mamo AG, Tarekegn G, Mekonnen A, Endale A (2022) Post-partum Lymphocytic Hypophysitis in Ethiopian Woman. J Obes Metab 5: 110. Doi: 10.4172/jomb.1000110

Copyright: © 2022 Mamo AG, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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