alexa Predictive Value of the TSH/FT4 Ratio in Women with Suspected PE or GH | OMICS International| Abstract

ISSN: 2376-127X

Journal of Pregnancy and Child Health

  • Research Article   
  • J Preg Child Health,
  • DOI: 10.4172/2376-127X.1000357

Predictive Value of the TSH/FT4 Ratio in Women with Suspected PE or GH

Megumi Fudaba*, Kazuharu Tanaka, Atsushi Matuski, Maya Komori, Takako Matsuki, Mie Tahara, Sachiyo Nishimoto, Koji Kajitani, Hiroaki Nakamura and Osamu Nakamoto
Department of Obstetrics and Gynecology, Osaka City General Hospital, , Japan
*Corresponding Author : Megumi Fudaba, Department of Obstetrics and Gynecology, Osaka City General Hospital, Osaka, Japan, Tel: 819033535919, Email: [email protected]

Received Date: Oct 19, 2017 / Accepted Date: Nov 02, 2017 / Published Date: Nov 09, 2017

Abstract

Objective: In the present study, we aimed to examine whether the TSH/FT4 ratio after the second trimester can predict the prevalence of preeclampsia (PE) or gestational hypertension (GH).

Study design: Retrospective case-control study.

Methods: We collected TSH and FT4 serum levels after the second trimester in 133 pregnant women with suspected PE or GH. Participants were divided into 2 groups, the PE+GH group and the non-PE+GH group and conducted the retrospective study for the two groups to evaluate the background and the prevalence of PE or GH were retrospectively evaluated.

Results: Among the participants in the PE+GH group, mean age, body mass index (BMI) at no pregnancy and BMI at delivery were 34.5 ± 6.7 years, 22.3 ± 3.9 kg/m2 and 26.0 ± 4.0 kg/m2, respectively. Among the participants in the non-PE+GH group, mean age, BMI at no pregnancy and BMI at delivery were 32.9 ± 5.5 years, 22.5 ± 4.8 kg/m2 and 26.1 ± 4.4 kg/m2, respectively. There were no significant differences observed between the two groups. The cutoff point of the TSH/FT4 ratio was 1.9 (sensitivity 0.45, specificity 0.81), which was derived from the receiver operating characteristic curve. The adjusted odds ratio of PE or GH prevalence was 3.60 (95% CI: 1.62-8.02).

Conclusion: The TSH/FT4 ratio after the second trimester may aid in the prediction of PE or GH prevalence.

Keywords: Preeclampsia; Gestational hypertension; TSH; FT4

Citation: Fudaba M, Tanaka K, Matuski A, Komori M, Matsuki T, et al. (2017) Predictive Value of the TSH/FT4 Ratio in Women with Suspected PE or GH. J Preg Child Health 4: 357. Doi: 10.4172/2376-127X.1000357

Copyright: ©2017 Fudaba M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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