Journal of Tuberculosis and Therapeutics
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  • Short Communication   
  • J Tuberc Ther 2017, Vol 2(1): 104

To Understand the Role of Heme Molecules in the Survival and Pathogenesis of Mycobacterium tuberculosis

Swati Meena and Laxman S Meena*
CSIR-Institute of Genomics and Integrative Biology, Council of Scientific and Industrial Research, , Mall Road, Delhi, India
*Corresponding Author : Laxman S Meena, CSIR-Institute of Genomics and Integrative Biology, Mall Road, Delhi-110007, India, Tel: 011-27666156, Fax: 011-27667471, Email: Laxmansm72@yahoo.com

Received Date: Jan 31, 2017 / Accepted Date: Feb 17, 2017 / Published Date: Feb 24, 2017

Abstract

Mycobacterium tuberculosis is an aerobic gram positive pathogen which causes deadly disease called tuberculosis (TB) which is still a major threat to life. Mycobacterium tuberculosis Pathogen enters in host by inhalation of air because these pathogens are present in air droplets released by other TB infected persons. It ultimately reaches to lung alveoli and gives rise to primary TB. In macrophages Mycobacterium replicates itself and increases its number in host cell. Artemisinin is a drug obtained from the plant Artemisia which target the heme molecule in mycobacterium and stop its replication.

Keywords: Mycobacterium tuberculosis; H37Rv; Rv0203; Heme molecule; Artemisia afra

Citation: Meena S, Meena LS (2017) To Understand the Role of Heme Molecules in the Survival and Pathogenesis of Mycobacterium tuberculosis. J Tuberc Ther 2: 104.

Copyright: © 2017 Meena S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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