alexa Recurrent Head Trauma: A Trigger of the Alzheimer Cascade or the Cause of an Independent Pathologic Entity? - An Explicative Case of Chronic Traumatic Encephalopathy Mimicking Alzheimer's Disease| Abstract
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Short Communication   
  • J Alzheimers Dis Parkinsonism 2017, Vol 7(6): 408
  • DOI: 10.4172/2161-0460.1000408

Recurrent Head Trauma: A Trigger of the Alzheimer Cascade or the Cause of an Independent Pathologic Entity? - An Explicative Case of Chronic Traumatic Encephalopathy Mimicking Alzheimer's Disease

Giulia Grande1, Daniela Galimberti2, Laura Maggiore3, Elio Scarpini2, Claudio Mariani3 and Carlo Lovati3*
1Department of Neurobiology, Aging Research Center, Care Sciences and Society (NVS), arolinska Institutet, Stockholm University, Stockholm, Sweden
2Neurology Unit, Department of Pathophysiology and Transplantation, Dino Ferrari Center, University of Milan, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy
3Clinical Neurology, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy
*Corresponding Author : Carlo Lovati, Department of Biomedical and Clinical Sciences, Clinical Neurology, University of Milan, Luigi Sacco Hospital, Milan, Italy, Tel: 00390239042317, Email: [email protected]

Received Date: Nov 30, 2017 / Accepted Date: Dec 13, 2017 / Published Date: Dec 20, 2017

Abstract

Repeated traumatic brain injuries have a negative impact on brain integrity and cognition. It was hypothesized that they could trigger the AD amyloidogenic cascade or they could represent a peculiar clinical entity labelled as “chronic traumatic encephalopathy”, CTE. To contribute in the understanding of this controversy we describe the case of a boxer with early onset dementia, reporting biomarkers and neuropsychological assessment with the effort to differentiate the AD diagnosis and CTE. We discuss, for each element, it’s possible role with regard to the opposite diagnostic directions and we highlight, on the example of our probable CTE patient, the necessity of better defined diagnostic criteria for the chronic traumatic encephalopathy.

Keywords: Traumatic brain injuries; Chronic traumatic encephalopathy; Alzheimer’s disease; Dementia

Citation: Grande G, Galimberti D, Maggiore L, Scarpini E, Mariani C, et al. (2017) Recurrent Head Trauma: A Trigger of the Alzheimer Cascade or the Cause of an Independent Pathologic Entity? - An Explicative Case of Chronic Traumatic Encephalopathy Mimicking Alzheimer’s Disease. J Alzheimers Dis Parkinsonism 7: 408. Doi: 10.4172/2161-0460.1000408

Copyright: © 2017 Grande G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Select your language of interest to view the total content in your interested language

Post Your Comment Citation
Share This Article
Relevant Topics
Article Usage
  • Total views: 1401
  • [From(publication date): 0-2017 - Dec 16, 2019]
  • Breakdown by view type
  • HTML page views: 1345
  • PDF downloads: 56
Top