Journal of Clinical & Experimental Pathology
Open Access

Small Lymphocytic Lymphoma Presenting as Multiple Lymphomatous Polyposis

¹Department of Pathology, Toranomon Hospital, Tokyo, Japan

²Pathology Project for Molecular Targets, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan

³Department of Hematology and Oncology, Graduate School of Medicine, the University of Tokyo, Japan

⁴Department of Pathology and Diagnostic Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

*Corresponding Author:

Yasunori Ota
Department of Pathology
Toranomon Hospital, Tokyo, Japan
E-mail: [email protected]

Received date: October 24, 2012; Accepted date: December 06, 2012; Published date: December 08, 2012

Citation: Ota Y, Takeuchi K, Kurokawa M, Fukayama M (2012) Small Lymphocytic Lymphoma Presenting as Multiple Lymphomatous Polyposis. J Clin Exp Pathol 2:132. doi: 10.4172/2161-0681.1000132

Copyright: © 2012 Ota Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Multiple Lymphomatous Polyposis (MLP) is characterized by multiple polyps with lymphoma invasion involving long segments of the Gastrointestinal (GI) tract. Most MLP are thought to represent Mantle Cell Lymphoma (MCL) of the GI tract. However, some follicular lymphomas, mucosa-associated lymphoid tissue lymphomas, and adult T-cell lymphomas [5] have been found to show a multiple polypoid appearance throughout long segments of the GI tract. We report a case with MLP associated with Small Lymphocytic Lymphoma (SLL). SLL in extranodal sites is difficult to diagnose and the clinical course is different from that of MCL. MCL has a more aggressive clinical course than Chronic Lymphocytic Leukemia or SLL (CLL/SLL). A median survival time of CLL/SLL is 7 to 10 years, while patients with MCL have a median survival of 3 years .