The Risk of Ileocolonic Perforation in Patients with Behet's Disease: Report of Three Cases and Review of the LiteratureMehmet Bektas1*, Cagdas Kalkan1, Irfan Soykan1, Ayse Boyvat2, Berna Savas3, Ethem Gecim4, Onur Keskin1, Ekin Kırcali1, Ali Tuzun1 and Necati Ormeci1
- *Corresponding Author:
- Mehmet Bektas
Ankara University School of Medicine
Department of Gastroenterology, Ibn-iSina Hospital
Sihhiye, Ankara-Turkey 06100
Fax: +90 312 363 6213
E-mail: [email protected]
Received date: March 22, 2014; Accepted date: April 25, 2014; Published date: April 30, 2014
Citation: Bektas M, Kalkan C, Soykan I, Boyvat A and Savas B, et al., (2014) The Risk of Ileocolonic Perforation in Patients with Behçet's Disease: Report of Three Cases and Review of the Literature. J Gastroint Dig Syst 4:184. doi:10.4172/2161-069X.1000184
Copyright: © 2014 Bektas M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction/Purpose: Intestinal Behcet’s disease may cause serious complications. Massive hemorrhage,
fistulisation and intestinal perforation are encountered complications in approximately 50% of patients suffering from
intestinal Behcet’s disease. Currently, there is not enough data inquiring iatrogenic ileocolonic perforation during
colonoscopy in patients with intestinal Behcet’s disease; therefore we aimed to study intestinal Behcet’s disease
patients who suffered perforation during or after colonoscopy.
Methods: A total of 2615 colonoscopic examinations were performed between May 2002 and December 2007.
Of these 2615 patients, main indication for colonoscopy was intestinal Behcet’s disease in 135 patients.
Results: In total 135 patients with Behcet’s patients were assessed with colonoscopy due to presumed
ileocolonic involvement. 8 out of 135 (5.9%) patients had ileal and colonic ulcers. 3 patients (2.22%) had iatrogenic
perforation, 2 of whom had profound ulcers in proximal colon and ileum. The third case had ulcers in sigmoid colon,
descending and transverse colon segments. All these 3 patients had undergone surgical intervention including ileal
resection and right hemicolectomy.
Discussion: Colonoscopic examination is commonly used in Behcet’s disease not only for diagnostic purposes
but also for surveillance of intestinal involvement in Behcet’s disease. Volcano-shaped ulcers are specially inclined
to perforate. Both clinicians and endoscopists should be alert against barotrauma applied during colonoscopy may
cause perforation. Also patients should be followed-up necessarily and in case of abdominal pain after colonoscopic
examination, colonic perforation should always be kept in mind.f