alexa Toxicity Effects of Both Alum and Poly-DADMAC on Nubian Goats Evita
ISSN: 2476-2067

Toxicology: Open Access
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Research Article

Toxicity Effects of Both Alum and Poly-DADMAC on Nubian Goats Evita

Amna Ahmed1, Samia Elbadwi2 and Ahmed Mohammed2*

1University of Medical Sciences & Technology, Faculty of Pharmacy, Khartoum, 12810 Sudan

2University of Khartoum, Department of Pharmacology & Toxicology, Khartoum, Sudan

*Corresponding Author:
Amna Ahmed
University of Medical Sciences & Technology
Faculty of Pharmacy, Khartoum, 12810 Sudan
Tel: +249912369706
Fax: +249183224799
E-mail: [email protected]

Received date: Augest 12, 2015 Accepted date: September 29, 2015 Published date: October 01, 2015

Citation: Ahmed A, Elbadwi S, Mohammed A (2015) Toxicity Effects of Both Alum and Poly-DADMAC on Nubian Goats Evita . Toxicol Open Access 1:101. doi:10.4172/2476-2067.1000101

Copyright: © 2015 Ahmed A et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Nubian goats were the animals tested for the toxicity of both alum and polydadmac blend of 1% alum and 1% polydadmac at 1:2 Clinical signs of tested goats showed interrupted salivation, vomiting, watery diarrhea, dullness, inappetance ,inability to move accompanied by hind limb paralysis and finally recumbency. On postmortem, and histopathological assessment, most vital organs were clearly affected. Serum concentrations of tested enzymes showed marked (P0<0.05-0.01) fluctuations in the test group of goats. The test group showed marked (P<0.01-0.001differences when evaluating their serum levels of metablites. Goats of test group 2 showed significant (P<0.05-0.01) changes when tested for serum levels of electrolytes. All serum values detected, showed normal values in the control goats.On evaluation of results, the water treatment with 1% alum and 1% polydadmac at 1:2 was considered toxic to Nubian goats.

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