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Toxicological Analysis of Oxybenzone Effects | OMICS International| Abstract

World Journal of Pharmacology and Toxicology
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  • Mini Review   
  • World J Pharmacol Toxicol 2023, Vol 6(2): 182
  • DOI: 10.4172/wjpt.1000182

Toxicological Analysis of Oxybenzone Effects

Affain Sufi*
Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Biology, Columbia University, New York, U.S.A
*Corresponding Author : Affain Sufi, Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Biology, Columbia University, New York, U.S.A, Email: affain.s@gmail.com

Received Date: Mar 03, 2023 / Published Date: Mar 30, 2023

Abstract

Oxybenzone is a new aquatic pollutant whose widespread use has made it easier to find in exposed biota’s body burdens and surface waters. In this review, the sub-deadly poisonousness impacts of oxybenzone were learned at the earth pertinent groupings of 0.6 and 5.2 μg/L (counting 0.01% DMSO as the dissolvable control). The metabolic physiology of larval zebra fish (Danio rerio) after 7 days of exposure (from 2 to 9 days post fertilization) was investigated using an integrated in vivo and in silico experimental strategy. Whole-organ respirometry revealed a statistically significant twofold increase in metabolic rate for the 0.6 g/L treatment group; however, there were no significant differences observed between the solvent control and the oxybenzone treatment level of 5.2 g/L. Functional categories related to metabolism (metabolic enzymes) and biological regulation (genome regulation, cell signaling) were found to be highly deregulated in the analysis of whole-transcriptase RNA-sequencing data.

Citation: Sufi A (2023) Toxicological Analysis of Oxybenzone Effects. World J Pharmacol Toxicol 6: 182. Doi: 10.4172/wjpt.1000182

Copyright: © 2023 Sufi A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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