alexa

GET THE APP

Uplc-Ms/Ms Method for The Simultaneous Determination of Plasma Catecholamines And Their Metabolites | OMICS International| Abstract
ISSN: 2168-9652

Biochemistry & Physiology: Open Access
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Perspective Article   
  • Biochem Physiol,

Uplc-Ms/Ms Method for The Simultaneous Determination of Plasma Catecholamines And Their Metabolites

Mahyar Yousefi
*Corresponding Author :

Mahyar Yousefi



Abstract

Phaeochromocytomas and paragangliomas (PPGLs) are rare tumors of adrenal chromaffin cells or extra-adrenal paraganglia. they're difficult to diagnose due to the non-specific clinical symptoms like hypertension, palpitations, flushing and sweating. Inappropriate catecholamines (CAs) production was normally used for the diagnosis of PPGLs within the clinical laboratory. Traditionally, 24-hour urine was used for analysis to permit for intermittent secretion of CAs by PPGLs. The guideline recommends screening of fractionated urinary metanephrines (MNs, the metabolites of CAs) or plasma free MNs using high performance liquid chromatography with electrochemical detection (HPLC-ECD) or liquid chromatography

Keywords: Plasma Catecholamines, Metabolites

Top