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Intravenous Leiomyomatosis that was Difficult to Distinguish in Treatment-Resistant Thrombosis Complicated with a Large Leiomyoma: A Case Report | OMICS International| Abstract

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  • Case Report   
  • Diagn Pathol Open 5: 174,
  • DOI: 10.4172/2476-2024.1000174

Intravenous Leiomyomatosis that was Difficult to Distinguish in Treatment-Resistant Thrombosis Complicated with a Large Leiomyoma: A Case Report

Yuki Yoshimura1,2, Kentaro Nakayama1*, Ruriko Fukushima1, Hitomi Yamashita1, Tomoka Ishibashi1, Masako Ishikawa1, Hiroki Sasamori1, Seiya Sato1 and Satoru Kyo1
1Department of Obstetrics and Gynecology, Shimane University, Shimane, Japan
2Department of Obstetrics and Gynecology, National Hospital Organization Hamada Medical Center, Shimane, Japan
*Corresponding Author : Dr. Kentaro Nakayama, Department of Obstetrics and Gynecology, Shimane University, Shimane, 6938501, Japan, Tel: (+81) 853-20-2268, Fax: (+81) 853-20-2264, Email: kn88@med.shimane-u.ac.jp

Received Date: Oct 20, 2020 / Accepted Date: Nov 03, 2020 / Published Date: Nov 10, 2020

Abstract

Background: Intravascular leiomyomatosis (IVL) is a rare benign tumor that grows within the veins, similar to cancer, without invading them.

Case presentation: We report the case of a 55-year-old woman who had a large leiomyoma (20 cm × 16 cm × 9 cm) and was scheduled for surgery.  Contrast-enhanced computed tomography was performed preoperatively and it revealed clots in the Inferior Vena Cava (IVC). This led to a diagnosis of deep venous thrombosis. Anticoagulation therapy was initiated, but the thrombus did not decrease in size. She was diagnosed with an organized thrombosis, and under general anesthesia which closed monitoring patients, total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. During the surgery, leiomyoma moved up to the blood vessel. We diagnosed IVL based on a histopathological examination.

Conclusion: The possibility of IVL should be amply considered when suspecting treatment-resistant thrombosis associated with a large leiomyoma.

Keywords: Intravenous leiomyomatosis; Deep venous thrombosis; Inferior vena cava

Citation: Yoshimura Y, Nakayama K, Fukushima R, Yamashita H, Ishibashi T, et al. (2020) Intravenous Leiomyomatosis that was Difficult to Distinguish in Treatment- Resistant Thrombosis Complicated with a Large Leiomyoma: A Case Report. Diagnos Pathol Open 5: 174. Doi: 10.4172/2476-2024.1000174

Copyright: © 2020 Yoshimura Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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