ISSN: 2161-1165

Epidemiology: Open Access
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  • Review Article   
  • Epidemiology (Sunnyvale) 2016, Vol 6(2): 233
  • DOI: 10.4172/2161-1165.1000233

Peritoneal Mesothelioma and Asbestos: Clarifying the Relationship by Epidemiology

Marty S. Kanarek* and Madalyn K. Mandich
Department of Population Health Sciences, School of Medicine and Public Health and the Nelson Institute for Environmental Studies, University of Wisconsin-Madison, USA
*Corresponding Author : Marty S. Kanarek, Department of Population Health Sciences, School of Medicine and Public Health, 610 N. Walnut Street, University of Wisconsin-Madison, USA, Tel: 608-262-1626, Email: mkanarek@wisc.edu

Received Date: Feb 24, 2016 / Accepted Date: Mar 23, 2016 / Published Date: Mar 29, 2016

Abstract

Peritoneal mesothelioma has been recognized for over a half century, but causality with asbestos of different fiber types and the incidence of this fatal tumor in relation to asbestos exposure dose still needs clarification. In order to help bring clarity, the most important studies on peritoneal mesothelioma, including a brief history, relationship to asbestos exposures, diagnostic issues and experimental studies are reviewed including case series, case-control, occupational, and registry epidemiology studies. This review concludes that all types of asbestos, including amphiboles and chrysotile, are causative for peritoneal mesothelioma. Many cases have been found in both males and females from asbestos exposures in occupational and neighborhood settings, shown in differing epidemiology study designs. It is clear that there is a causal relationship between all types of asbestos at all dose levels for peritoneal mesothelioma and no threshold of exposure to asbestos appears safe.

Keywords: Asbestos; Mesothelioma; Peritoneal mesothelioma; Epidemiology

Citation: Kanarek MS, Mandich MK (2016) Peritoneal Mesothelioma and Asbestos: Clarifying the Relationship by Epidemiology. Epidemiology (Sunnyvale) 6:233. Doi: 10.4172/2161-1165.1000233

Copyright: © 2016 Kanarek MS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Review summary

  1. Ramon Eustis
    Posted on Oct 03 2016 at 5:07 pm
    I think that that the inference of 'causality' is far too strong, based on epidemiological evidence. Other criteria must be considered to make this step.
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