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Surgical Management of Severe Head Injury with Cerebral Herniation
Background: Can decompressive craniectomy improve the outcome of patients with severe brain injury and cerebral herniation following blunt trauma? Objective: To assess the efficiency of decompressive craniectomy in the management of severe brain injury with computed tomographic (CT) evidence of cerebral herniation following blu.. Read More
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Endovascular Treatment of Infective Cerebral Aneurysms an Egyptian Experience
Purpose: To evaluate the endovascular treatment offered in our institution for five cases harboring infective cerebral aneurysms. The technique and clinical evolution are described. Material and methods: Five patients’ four men and a woman have been referred to our institution for endovascular treatment of infective cereb.. Read More
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Experimental Models of Microvascular Immunopathology: The Example ofCerebral Malaria
Human cerebral malaria is a severe and often lethal complication of Plasmodium falciparum infection. Complex host and parasite interactions should the precise mechanisms involved in the onset of this neuropathology. Adhesion of parasitised red blood cells and host cells to endothelial cells lead to profound endothelial alteratio.. Read More
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Postencephalitic Parkinsonism in a Patient with Mumps Infection: A Case Report
In 1917, Von Economo described a disease named "Encephalitis Lethargica" which affected a large number of patients across the world in an epidemic between 1916 and 1927. It's spread paralleled with the spread of the pandemic influenza, but Von Economo and the contemporary authors did not believe it to be a post-influen.. Read More
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Sodium Oxybatefor Narcolepsy with Cataplexy– Cost-Effective Analysis
Objective: To assess the cost-effectiveness of sodium oxybate plus antidepressants and stimulants compared with the current standard treatment for narcolepsy with cataplexy in the UK. Methods: We developed a Markov model to assess the costs and benefits of sodium oxybate plus antidepressants and stimulants or current standard tr.. Read More
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Limbic Encephalitis Caused By Neurospyhilis in a HIV-Positive Male: Case Report and Review
Neurosyphilis can present with a wide range of different presentations. For this reason, it has been called the “the great imitator”. Limbic encephalitis mimicking HSV encephalitis is an under recognized manifestation of neurosyphilis. Co-infection with HIV may alter the course of neurosyphilis and cause more atypica.. Read More
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Protective Effect of Ginger (Zingiber officinale) on Alzheimer's disease Induced in Rats
The possible protective effect of Ginger on Alzheimer’s disease induced in rats was investigated. Ninety rats were used as follows: control group, AD protective group using AlCl3, 3rd, 4th, and 5th groups rats were received orally Rivastigmine, Ginger (108 and 216 mg/kg/day) respectively, for two weeks followed by combinat.. Read More
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Background: Cognitive function of HIV-infected patients in Nigeria has been studied using the community screening instrument for dementia (CSI-D) battery. However, its ability to detect HIV-associated neurocognitive disorders (HAND) is unclear. The study assessed the CSI-D battery in detecting HAND. Methods: Age, sex and educat.. Read More
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Medical Management of Trigeminal Neuralgia: A Review
Trigeminal neuralgia (TN) is a severe chronic pain syndrome characterized by an excruciating, brief electric shock like paroxysmal pain in one or more divisions of the trigeminal nerve. The pain, also known as “tic douloureux”, is paroxystic and very severe. It can be triggered by a light cutaneous stimulus on a much.. Read More
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Laryngeal Histoplasmosis–Description of Two Cases Autochthonous In Brazil and Review of Literature
Histoplasmosis is primarily an inhalation-acquired mycosis with rare cases of cutaneous inoculation histoplasmosis being described. Although it is the third potentially fatal opportunistic mycosis in patients with AIDS, histoplasmosis infection involving the larynx is a rare manifestation. Mucosal lesions may mimic tuberculosis .. Read More
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Role of Immunological Markers in the Diagnosis, Treatment and Follow-Up of Human Neurocysticercosis
Neurocysticercosis is the commonest parasitic disease of the nervous system. Its clinical manifestations are highly variable ranging from asymptomatic disease to recurrent seizures and multisystem involvement. The imaging findings of neurocysticercosis although typical are not diagnostic for the disease and can be confused lesio.. Read More
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Cranial Epidural Abscess Successfully Treated with Conservative Measures:Case Report
Acute Bacterial Meningitis (MBA) is important causes of morbidity and mortality. Suppurative complications of MBA are frequent, especially in children, but are poorly described in the literature. Epidural abscess usually occurs as a result of otorhinolaryngological infections, cranial trauma or neurosurgical procedures and is ra.. Read More
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Pituitary Abscess in Post Spinal Anesthesia
We report a case of a 52 year old man, operated under spinal anesthesia for prostate adenoma. He presented two days after this surgery signs of intracranial hypertension. Magnetic resonance imaging of the brain revealed a pituitary abscess. The patient underwent sellar decompression via nasal transsphenoidal route with complete .. Read More
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Cognitive Outcome in HIV-Individuals with cART Containing ABC/AZT
Objective: The aim of our study was to investigate whether an antiretroviral regimen including ABC and AZT can be used to improve or maintain neuropsychological and neurophysiological parameters and effectively suppress HIV Viral Load (VL) in the Cerebrospinal Fluid (CSF). Design: An open prospective observational study Method.. Read More
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Dengue Viral Infection Complicated by Acute Transverse Myelitis
Background: Dengue is increasingly being recognized as an emerging infectious disease in Southeast Asia, resulting in spectrum of clinical presentations. Neurological complications secondary to dengue are rare and the exact incidence is unknown. Case report: A 43-year old Chinese male was initially admitted for dengue and then .. Read More
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Toxoplasma gondii is a ubiquitous parasite infecting up to 30% of the population worldwide. Most individuals infected with T. gondii harbor a chronic infection that persists for the lifetime of the host with the parasite located predominantly in neural and muscular tissue. In some immune competent hosts however, chronic infectio.. Read More
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Ocular Disease Associated with West Nile Virus Infection
Chorioretinal involvement, frequently asymptomatic and self-limited, is common in patients with West Nile virus (WNV) infection associated with neurologic illness. A bilateral multifocal chorioretinitis, with typical clinical and fluorescein angiographic features, is the most common finding, but numerous other ocular manifestati.. Read More
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Predictors of Drug Induced Hepatotoxicity in Tuberculous Meningitis
Background: There is paucity of studies on Drug Induced Hepatitis (DIH) following Anti-Tubercular Therapy (ATT) in the patients with Tuberculosis Meningitis (TBM). In this study, the frequency, spectrum and predictors of DIH in TBM have been reported. Methods: 150 TBM patients without history of prior liver disease were prospec.. Read More
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Acute Spinal Syndrome Due to Thoracic Vertebral Brucellosis: A Case Report
Introduction: Brucellosis is a zoonotic infection caused by brucella species. It is an endemic disease in the Mediterranean region. It may affect different organ systems with osteoarticular involvement in the form of peripheral arthritis, sacroiliitis and spondylitis being the most common and serious complication of the disease .. Read More
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Background: The processing of cassava into Gari comes with a lot of environmental as well as occupational hazards to the processors, and even the consumers. This study aimed at describing the occupational hazards, health problems and peak expiratory flow rate [PEFR] of local gari processors in a rural community in Nigeria. Meth.. Read More
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