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We report a case of a 52 year old man, operated under spinal anesthesia for prostate adenoma. He presented two days after this surgery signs of intracranial hypertension. Magnetic resonance imaging of the brain revealed a pituitary abscess. The patient underwent sellar decompression via nasal transsphenoidal route with complete evacuation and irrigation of the pituitary abscess. The patient received appropriate antibiotics for 6 weeks. The histopathology confirmed the presence an abscess cavity featuring multiple fragments of fibrous. Staphylococcus aureus was identified on culture.