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Dr. Matei obtained my Ph.D. in Cellular and Molecular Biology from the University of Toronto, studying the molecular mechanisms that render developing lymphocytes exquisitely susceptible to malignant transformation. She then went on to study the function of tumor-derived exosomes in tumorigenesis and metastasis under the mentorship of Dr. David Lyden, at Weill Cornell Medicine. She has expertise in cancer metastasis and exosome biology and combines innovative basic tumor biology research with translational studies, relating basic discoveries to advances in patient treatments. Her current research focuses on the crosstalk between tumor cells and the local and distant tumor microenvironment via exosomes. Specifically, she is interested in deciphering the role of exosomes in mediating the crosstalk between the host immune system and the tumor, and the mechanisms through which exosomes coax the immune system to contributes to malignant progression.
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