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My primary research interests focus on drug absorption, metabolism, and drug-drug interaction. In order to understand the ADME of drugs, I am using a variety of biological models including Caco-2 cell, intestinal perfusion, microsomes and S9 fractions that are enriched in metabolic enzymes and whole animals such as mice and rats to determine the ADME performances of active components in the natural products. I am also interested in the analysis of herbal medicines. I have been engaged in many different areas of herbal research ranging from screening to isolation, structure elucidation, partial and total synthesis of bioactive molecules and characterizing the criteria of herbal and herbal mixtures.
Disposition of components in herbal medicines.
Bioanalysis of small molecules (drug and drug metabolites) and large molecules (drug metabolism enzymes and transporters)
Identification and total synthesis of bioactive natural products
|Bryan K. Kee, Michael J. Overman, Song Gao, Pavan Kumar Chityala, Yu He, Pankajini Mallick, Ming Hu, Romi Ghose and Rongjin Sun|
|: J Clin Exp Pathol, 8: 350|
|Xisong Gao, Xiaoning Li, Chao Qian, Feng Li, Yu Zhang, Lianfeng Dang, Xueqian Xiao, Feng Liu, Haima Li and Xiujuan Zhang|
|Research Article: Cell Mol Biol 2016, 62:145|
|Song Gao, Shanglian Bao, Christine B Chung, Graeme M Bydder and Jiang Du|
|Research Article: OMICS J Radiology 2013, 2: 118|
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