alexa Critical Appraisal of Subgroup Analysis | Open Access Journals
ISSN: 2471-9919
Evidence based Medicine and Practice
Like us on:
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Critical Appraisal of Subgroup Analysis

Leonardo Roever*

Department of Clinical Research, Federal University of Uberlândia, Uberlândia, Brazil

Corresponding Author:
Roever L
Department of Clinical Research
Av Pará, 1720 - Bairro Umuarama
Uberlândia-MG-CEP 38400-902, Brazil
Tel: +553488039878
E-mail: [email protected]

Received date: 08 January, 2016; Accepted date: 15 January, 2016; Published date: 22 January, 2016

Citation:Roever L, Oliveira BFG (2016) Critical Appraisal of Subgroup Analysis 1:e115. doi:10.4172/2471-9919.1000e115

Copyright: © 2016 Roever L. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Evidence based Medicine and Practice

Introduction

In the subgroup analysis is performed by separating the data for patient subgroups, such as those in different stages, with different comorbidities and ages. The Table 1 shows the checklist needed to make a critical analysis of subgroup analysis [1-8].

Appraisal questions

The hypothesis was before or after the analysis?

The difference between subgroups was one of a small number of hypotheses tested effects?

The difference between the subgroups is suggested by comparison intra studies?

What is the magnitude of the difference between subgroups?

The difference between subgroups is consistent among the analysed studies?

The difference between subgroups is statistically significant? The appropriate statistical test was used?

There is external evidence that supports the hypothesis of difference between subgroups?

There is constant interaction between the results found and previous studies?

Conflicts of interest are declared.

Rate the overall methodological quality of the study, using the following as a guide:
High quality (++): Majority of criteria met. Little or no risk of bias.
Acceptable (+): Most criteria met. Some flaws in the study with an associated risk of bias.
Low quality (-): Either most criteria not met, or significant flaws relating to key aspects of study design.
Reject (0): Poor quality study with significant flaws. Wrong study type. Not relevant to guideline.

Table 1: Critical appraisal of subgroup analysis.

Use this checklist can improve the evaluation of subgroup analysis.

References

Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Recommended Conferences

Article Usage

  • Total views: 7939
  • [From(publication date):
    April-2016 - Oct 22, 2017]
  • Breakdown by view type
  • HTML page views : 7867
  • PDF downloads :72
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords