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Optical Coherence Tomography in Laryngology: Clinical Use
ISSN: 2161-119X

Otolaryngology: Open Access
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  • Otolaryngol

Optical Coherence Tomography in Laryngology: Clinical Use

Erianna Alam*
*Corresponding Author: Erianna Alam, Department of Otolaryngology and Head and Neck Surgery, 284697 Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, Email: [email protected]

Received: 03-Dec-2021 / Accepted Date: 16-Dec-2021 / Published Date: 23-Dec-2021


A procedure called optical cognizance tomography (OCT) has been produced for noninvasive cross-sectional imaging in organic frameworks. OCT utilizes low-intelligibility interferometry to create a two-dimensional picture of optical dissipating from inward tissue microstructures in a manner that is comparable to ultrasonic heartbeat reverberation imaging. OCT has longitudinal and parallel spatial goals of a couple of micrometers and can recognize reflected signs as little as ~10−10 of the occurrence optical power. Tomographic imaging is shown in vitro in the peripapillary space of the retina and in the coronary supply route, two clinically important models that are representative of transparent and turbid media, respectively

Keywords: Endoscopy; Imaging; Larynx; Optical coherence tomography; Otolaryngology; Vocal folds


Optical soundness tomography (OCT) is an arising imaging methodology that joins a low-intelligence light source and an interferometer to create cross-sectional high-goal pictures of living tissues. OCT works similarly to ultrasonography yet rather than sound uses close infrared light to recognize variety in tissue optical properties. Clinical OCT gadgets have a pivotal goal of roughly 10 μm and a greatest profundity infiltration of 2 to 3 mm, albeit 1 to 2 mm is more average in light of the fact that most biologic tissues are turbid. This innovation has been broadly utilized in ophthalmology for assessment of the retina, cornea, and macula and as an aide in waterfall surgery. OCT has been assessed in different claims to fame, including dermatology, cardiology, pulmonology, gastroenterology, urology, and nervous system science, albeit basically utilizing research OCT frameworks planned and developed by experts in photonic advancements at scholastic clinical focuses Tomographic imaging methods, for example, x-beam registered tomography attractive reverberation imaging and ultrasound imaging have tracked down inescapable applications in medication.

Every one of these methods estimates an alternate actual property and has a goal and entrance range that demonstrate favorable for explicit applications. In this report, we examine OCT. With this procedure it is feasible to perform noninvasive cross-sectional imaging of inward constructions in natural tissues by estimating their optical reflections [1].

In the head, neck, and upper aerodigestive lot, clinical OCT has zeroed in on assessment of the larynx, with one objective: to recognize harmless from microinvasive disease that has abused the honesty of the cellar film (BM). Some work has zeroed in on utilizing OCT to perform picture directed treatment of the larynx, albeit the outcomes have been blended. It has additionally been utilized coupled to a careful magnifying instrument, permitting without hands OCT all the while with infinitesimal perception of the vocal ropes. All the more as of late, we spearheaded the utilization of OCT to picture both the neonatal and the pediatric aviation route fully intent on analyzing changes in the subglottis following delayed intubation. OCT has likewise been utilized to picture the center ear and thyroid gland. The oral hole has been concentrated extensively utilizing OCT and is explored somewhere else.

The most clinical OCT studies have involved the utilization of frameworks planned and worked by research bunches zeroed in on improving the goal, picture procurement rates, and usefulness of this early imaging methodology. As of not long ago, there has not been an industrially accessible turnkey OCT framework for use in the head and neck, and most investigations to date have utilized examination gadgets planned and developed in college optics labs. At University of California Irvine, we have had a functioning OCT research program at the Beckman Laser Institute and Medical Clinic for north of 15 years, with more than 7 years of clinical experience on OCT imaging in the head and neck in human subjects. Our examinations to date have utilized just OCT frameworks planned and developed in our labs. The target of this review was to give our experience utilizing the main financially accessible OCT gadget intended to picture the larynx among different applications and to contrast its utilization and our past experience in north of 200 patients utilizing research OCT frameworks [2,3].

Patient Population

OCT imaging was acted in 33 patients going through upper aero digestive parcel endoscopy under broad sedation, under the aegis of the Institutional Review Board at the University of California Irvine. Two subjects were imaged twice during two separate activities. 21 patients (64%) were male and 12 patients (36%) were female. The normal age was 53 years (range 18–86 years). Imaging commonly expected 3 to 5 minutes of extra careful time [4].

OCT System

A financially accessible clinical imaging framework (Niris, Imalux Corporation, Cleveland, OH) was utilized to analyze every understanding. This versatile time-space OCT system34 utilizes a lowsoundness close infrared light source to obtain on-going pictures of 200 × 200 pixels at a most extreme casing pace of 0.7 Hz. The spatial profundity goal of the framework is 10 to 20 μm, with a profundity filtering scope of 2.2 mm. Practically speaking, attributable to the turbidity of living tissues, filtering profundity is just around 1.5 mm. The sidelong goal is 25 μm, with a horizontal filtering scope of 1.5 to 2.5 mm. In OCT frameworks, sidelong goal is diffraction restricted, while hub goal relies upon the soundness length of the light sources. It utilizes a 2.7 mm distance across reusable adaptable test to acquire the pictures. To the client, the test shows up as a solitary, minimal instrument; notwithstanding, it encases a solitary mode optical fiber, which is filtered this way and that inside by a solenoid [5].


  1. Tarasov AP, Persheyev S, Rogatkin DA (2021) Exact analytical solutions and corresponding Monte Carlo models for the problem of light transport in turbid media with continuous absorption and discrete scattering at the single scattering approximation. J Quant Spectrosc Radiat Transf 271: 107741.
  2. Wang L, Shen M, Chang Q, Shi C (2021) Automated delineation of corneal layers on OCT images using a boundary-guided CNN. Pattern Recognition 120: 108158.
  3. Park SO, Kwon O, Kim Y, Cha SK (2021). Mind control attack: Undermining deep learning with GPU memory exploitation. Comput Secur 102: 102115.
  4. Mathialagan P, Chidambaranathan M (2021) Computer vision techniques for Upper Aero-Digestive Tract tumor grading classification–Addressing pathological challenges. Pattern Recognit Lett 144: 42-53.
  5. Zhang X, Cheng L (2021) Broadband and low frequency sound absorption by Sonic black holes with Micro-perforated boundaries. J Sound Vib 512: 116401.

Citation: Alam E (2021) Optical Coherence Tomography in Laryngology: Clinical Use. Otolaryngol (Sunnyvale) S8: 003.

Copyright: © 2021 Alam E. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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