alexa A Clinical Study on the Relationship Between Lymph Nodes Metastasis in Early Gastric Carcinoma and Clinicopathological Factors and Reasonable Treatment Options | Abstract
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

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Research Article

A Clinical Study on the Relationship Between Lymph Nodes Metastasis in Early Gastric Carcinoma and Clinicopathological Factors and Reasonable Treatment Options

Xin Zhang, Rui Zheng, Guo Wei, Jian-wei Bi and Ming-Ming Nie*

Department of General Surgery, Changhai Hospital, The Second Military Medical University, Xiangyin Road, Shanghai 200433, PR China

Corresponding Author:
Ming-Ming NIE
Department of General Surgery, Changhai Hospital
The Second Military Medical University
Xiangyin Road, Shanghai 200433, PR China
E-mail: [email protected]

Received Date: June 23, 2013; Accepted Date: August 09, 2013; Published Date: August 12, 2013

Citation: Zhang X, Zheng R, Wei G, Bi Jw, Nie MM (2013) A Clinical Study on the Relationship Between Lymph Nodes Metastasis in Early Gastric Carcinoma and Clinicopathological Factors and Reasonable Treatment Options. J Gastroint Dig Syst S1:007. doi: 10.4172/2161-069X.S1-007

Copyright: © 2013 Zhang X, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective: To investigate the rule of lymph node metastasis in early gastric cancer , in order to provide a reference for the reasonable treatment options.

Method: To retrospectively analyze the clinical data of 271 cases of EGC patients from October 2005 to October 2011.

Results: Both univariate analysis and multivariate analysis results show that tumor size, pathological classification and depth of invasion are correlated with lymph node metastasis. The further analysis of the rate of lymph node metastasis shows that lymph node metastasis cannot be found in the patients with differentiated tumor of which the size is below 3.0cm when tumor invades mucosal layer; at the same time, lymph node metastasis cannot be found in the patients with undifferentiated tumor whose size is below 2.0cm as well. However, lymph node metastasis occurs in all the sorts when tumor invades submucosal layer.

Conclusion: Tumor size, invasive depth, pathological classification, and lymphatic tube invasion were closely related to lymph node metastasis in patients with early gastric cancer, patients with early gastric cancer are recommended to have a preoperative Endoscopic Ultrasonographic (EUS) scan as well as pathological screenings for deciding the most appropriate type of surgery.

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