A Pilot Study of Induction Triplet Chemotherapy Followed by Minimally Invasive Surgery for Stage 3-4 Resectable Oropharyngeal Cancer
- *Corresponding Author:
- Krishna Rao
Simmons Cancer Institute at Southern Illinois University School of Medicine
315 W. Carpenter St., PO Box 19678, Springfield, IL 62794-9678, USA
E-mail: [email protected]
Received date: Apr 10, 2015; Accepted date:: May 19, 2015; Published date:: May 26, 2015
Citation: Rao K, Robinson K, Malone J, Clausen C, Shevlin B, et al (2015) A Pilot Study of Induction Triplet Chemotherapy Followed by Minimally Invasive Surgery for Stage 3-4 Resectable Oropharyngeal Cancer . Otolaryngol (Sunnyvale) 5: 196. doi:10.4172/2161-119X. 1000196
Copyright: © 2015 Rao K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The current study reports the results of an open label pilot study evaluating a novel treatment protocol for patients with locally advanced head and neck cancer. Patients received induction chemotherapy and those who had a clinical complete response to induction chemotherapy were offered trans-oral nidusectomy for the primary lesion and neck node dissection. If a pathologic complete response was achieved, patients were then observed. Patients not achieving a clinical or pathologic complete response to induction therapy were subsequently treated with chemoradiation.